In the aquatic environment, the interaction between environmental pollution is very complex, including pesticides and antibiotics are dominant. However, most studies only focus on the toxic effects of individual, not composite. In this study, the effect of sub-chronic exposure sipermetrin (CMN, 0.65 mg / L), sulfamethoxazole (SMZ, 0.30 mg / L) and mix them in the grass crap (Ctenopharyngodon idellus) was investigated. Brain tight junctions, and indices of oxidative stress associated with apoptosis was determined after 42 days of exposure. In terms of brain function, acetyl cholinesterase (AChE) activity was significantly inhibited by CMN, SMZ and mix them during the period of exposure. clear histological damage of cellular and subcellular levels was also observed, which is further confirmed by decreased levels of tight junction proteins. Malondialdehyde (MDA) and 8-hydroxy-2-deoxyguanosine (8-OHdG) significantly increased contents of individual compounds and mixtures, where the content of glutathione (GSH) is shown the opposite trend. In the mechanism, nuclear factor (erythrocytes derived 2) as 2 (Nrf2) pathway is activated, which can trigger cell protection to cope with CMN and SMZ exposure. However, apoptosis was also detected on the mRNA level and histochemistry. In general, both exogenously induced the same biological response. Neurotoxicity of CMN reinforced by SMZ associated with this index in many cases and vice versa. This study will reveal the risk of co-ecological potential of pesticides and antibiotics in aquatic organisms, and provide the basic data for the assessment of safety and risk.
Long non-coding RNAs GHET1 / miR-105 / RAP2B axis regulates the development of acute myeloid leukemia
Background: To explore the molecular mechanism of biological effects and potential long non-coding RNA (lncRNA) gastric carcinoma proliferation increases transcript 1 (GHET1) in acute myeloid leukemia (AML). Methods: Fluorescence in situ hybridization performed to determine the location GHET1. Quantitative polymerase chain reaction (qPCR) was performed to verify the RNA expression. GHET1 excess and knockdown achieved by transfection of the expression vector or short hairpin RNA. Western blotting, qPCR, Cell Counting Kit-8 assay, JC-1 staining and flow cytometry was conducted to measure the function GHET1. Dual luciferase reporter assay was conducted to confirm the relationship between microRNA 105 (miR-105) and Ras-related protein Rap-2B (RAP2B). Results: GHET1 localized in the nucleus of the cell line NB4. Expression GHET1 appointed in AML cell lines compared with normal bone marrow mononuclear cells. GHET1 knockdown led to inhibition of proliferation and promoted differentiation and apoptosis of AML cell lines. Subsequently, directly tied GHET1 miR-105 and miR-105 downregulated expression. MiR-105 suppressed excessive proliferation and induction of differentiation and apoptosis of AML cell lines. Additionally, RAP2B confirmed to be the target of miR-105 gene and demonstrated an inverse correlation between the level of their expression in AML cell lines; when miR-105 increased, the rate of Rap-2B decreases and vice versa. Conclusion: This study shows that GHET1 / miR-105 / Rap2B axis may be important signaling pathways involved in the development of AML.
external stimuli is a powerful tool that Nature uses to control the function and activity of proteins. For example, during viral entry and exit, the pH variation is known to trigger large conformational changes of proteins. In Nature, as well as electron transfer (ET) ET protein properties affected by pH-induced conformational changes. In this work, 3 10 -helix conversion pH controlled, reversible for α-helix (of acidic pH values were very basic and otherwise) of the peptide supramolecular systems are built on a gold surface is described.
Causal Relationship between Plasma Adiponectin and Body Mass Index: One-and two-sample two-way Mendelian Randomization Analysis on 460 397 Individuals
Background: Adiponectin is a protein hormone produced by adipocytes may play an important role in obesity. However, a causal association between plasma adiponectin and body mass index (BMI) is still uncertain. We tested the hypothesis that (a) plasma adiponectin and BMI were inversely associated observational, (b) genetically high BMI is associated with lower plasma adiponectin, and (c) genetic plasma adiponectin are associated with a lower BMI.
Methods: Information about 108 896 people from the Copenhagen General Population Study used in the Mendelian randomization analysis sample observational and a two-way, using the five genetic variants for BMI and 3 for adiponectin. For independent confirmation, information about 322 154 people from the GIANT consortium, and 29 347 people from the consortium ADIPOGen Mendelian randomization used in the analysis of two samples in two directions, using 68 genetic variants for BMI and 14 for adiponectin.
Results: In the observational analysis, an increase of 1 kg / m2 in BMI was associated with a 0.44 ug / mL (95% confidence interval: -0.46, -0.42) in plasma adiponectin, while an increase of 1 mg / mL in adiponectin plasma is associated with -0.11 kg / m2 (-0.12, -0.11) in BMI. In the causal genetic analysis, no relationship was observed between BMI and plasma adiponectin and vice versa. In the sample of Mendelian randomization analysis, 1 kg / m2 increase in BMI is determined genetically associated with -0.13 ug / mL (-0.53, 0.28) in plasma adiponectin, while the 1 mg / mL increase in genetically determined on plasma adiponectin was associated with a 0.01 kg / m2 (-0.05, 0.07) in BMI. As expected in the two-sample Mendelian randomization analysis was 0.03 mg / mL (-0.02, 0.07) and 0.03 kg / m2 (-0.02, 0.07), respectively.
 LSZ-102 |
|||
| HY-111486 | MedChemExpress | 50mg | EUR 3321 |
 MM-102 |
|||
| HY-12220 | MedChemExpress | 10mg | EUR 298 |
 IAXO-102 |
|||
| HY-125171 | MedChemExpress | 50mg | EUR 1944 |
 PPQ-102 |
|||
| B3504-10 | ApexBio | 10 mg | EUR 242 |
PPQ-102 |
|||
| B3504-5 | ApexBio | 5 mg | EUR 151 |
PPQ-102 |
|||
| B3504-50 | ApexBio | 50 mg | EUR 863 |
 PM 102 |
|||
| B5517-1 | ApexBio | 1 mg | EUR 601 |
MM-102 |
|||
| B1582-2 | ApexBio | 2 mg | EUR 128 |
|
Description: MM-102 is an antagonist of MLL1 with IC50 value of 2.4nM [1].Mixed lineage leukemia 1 (MLL1) is a histone H3 lysine 4 (H3K4) methyltransferase. |
|||
MM-102 |
|||
| B1582-20 | ApexBio | 20 mg | EUR 593 |
|
Description: MM-102 is an antagonist of MLL1 with IC50 value of 2.4nM [1].Mixed lineage leukemia 1 (MLL1) is a histone H3 lysine 4 (H3K4) methyltransferase. |
|||
MM-102 |
|||
| B1582-5 | ApexBio | 5 mg | EUR 212 |
|
Description: MM-102 is an antagonist of MLL1 with IC50 value of 2.4nM [1].Mixed lineage leukemia 1 (MLL1) is a histone H3 lysine 4 (H3K4) methyltransferase. |
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-FAM [5-(and-6)-Carboxyfluorescein] *CAS 72088-94-9*) 5(6)-FAM [5-(and-6)-Carboxyfluorescein] *CAS 72088-94-9* |
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| 102 | AAT Bioquest | 25 g | EUR 876 |
 p38 antibody |
|||
| 70R-51505 | Fitzgerald | 100 ul | EUR 268 |
|
Description: Purified Polyclonal p38 antibody |
|||
p38 antibody |
|||
| 70R-51506 | Fitzgerald | 100 ul | EUR 287 |
|
Description: Purified Polyclonal p38 antibody |
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 anti-p38 |
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| YF-PA11120 | Abfrontier | 50 ug | EUR 363 |
|
Description: Mouse polyclonal to p38 |
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anti-p38 |
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| YF-PA11121 | Abfrontier | 100 ug | EUR 403 |
|
Description: Rabbit polyclonal to p38 |
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anti-p38 |
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| YF-PA23519 | Abfrontier | 50 ul | EUR 334 |
|
Description: Mouse polyclonal to p38 |
|||
anti-p38 |
|||
| YF-PA23520 | Abfrontier | 50 ul | EUR 334 |
|
Description: Mouse polyclonal to p38 |
|||
anti-p38 |
|||
| YF-PA23521 | Abfrontier | 50 ul | EUR 334 |
|
Description: Mouse polyclonal to p38 |
|||
 p38 Antibody |
|||
| abx236076-100ug | Abbexa | 100 ug | EUR 481 |
p38 Antibody |
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| 20-abx133223 | Abbexa |
|
|
p38 Antibody |
|||
| 20-abx141038 | Abbexa |
|
|
p38 Antibody |
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| 20-abx007541 | Abbexa |
|
|
p38 Antibody |
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| 35478-100ul | SAB | 100ul | EUR 390 |
 p38 protein |
|||
| E20-80078 | EnoGene | 20ug | EUR 408 |
p38 protein |
|||
| E20-80079 | EnoGene | 20ug | EUR 408 |
p38 Antibody |
|||
| 48644-100ul | SAB | 100ul | EUR 333 |
p38 Antibody |
|||
| 48644-50ul | SAB | 50ul | EUR 239 |
) MM-102 (TFA) |
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| HY-12220A | MedChemExpress | 10mM/1mL | EUR 263 |
 BP-1-102 |
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| HY-100493 | MedChemExpress | 100mg | EUR 1345 |
 Inhibitor) SB-203580 p38 MAPK(p38 MAP kinase) Inhibitor |
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| E1B1863 | EnoGene | 1mg | EUR 161 |
 p38 beta, Active |
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| 7763-100 | Biovision | EUR 4345 | |
p38 beta, Active |
|||
| 7763-5 | Biovision | EUR 370 | |
 p38 MAPK antibody |
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| 70R-33398 | Fitzgerald | 100 ug | EUR 327 |
|
Description: Rabbit polyclonal p38 MAPK antibody |
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p38 MAPK antibody |
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| 70R-33400 | Fitzgerald | 100 ug | EUR 327 |
|
Description: Rabbit polyclonal p38 MAPK antibody |
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 P38 MAPK antibody |
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| 70R-34325 | Fitzgerald | 100 ug | EUR 327 |
|
Description: Rabbit polyclonal P38 MAPK antibody |
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P38 MAPK antibody |
|||
| 70R-34327 | Fitzgerald | 100 ug | EUR 327 |
|
Description: Rabbit polyclonal P38 MAPK antibody |
|||
 p38 MAPK Antibody |
|||
| AF6455 | Affbiotech | 200ul | EUR 304 |
|
Description: p38 MAPK Antibody detects endogenous levels of total p38 MAPK. |
|||
p38 MAPK Antibody |
|||
| AF6456 | Affbiotech | 200ul | EUR 304 |
|
Description: p38 MAPK Antibody detects endogenous levels of total p38 MAPK. |
|||
p38 MAPK Antibody |
|||
| AF6457 | Affbiotech | 200ul | EUR 304 |
|
Description: p38 MAPK Antibody detects endogenous levels of total p38 MAPK. |
|||
p38 MAPK Antibody |
|||
| ABF6456 | Lifescience Market | 100 ug | EUR 438 |
) Anti-p38 (3D5) |
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| YF-MA12551 | Abfrontier | 200 ul | EUR 363 |
|
Description: Mouse monoclonal to p38 |
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) Anti-p38 (1C9) |
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| YF-MA12552 | Abfrontier | 100 ug | EUR 363 |
|
Description: Mouse monoclonal to p38 |
|||
 anti-Crk p38 |
|||
| YF-PA11088 | Abfrontier | 50 ul | EUR 363 |
|
Description: Mouse polyclonal to Crk p38 |
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anti-Crk p38 |
|||
| YF-PA11089 | Abfrontier | 50 ug | EUR 363 |
|
Description: Mouse polyclonal to Crk p38 |
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anti-Crk p38 |
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| YF-PA11090 | Abfrontier | 100 ug | EUR 403 |
|
Description: Rabbit polyclonal to Crk p38 |
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 anti-AIMP2/p38 |
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| YF-PA15507 | Abfrontier | 50 ug | EUR 363 |
|
Description: Mouse polyclonal to AIMP2/p38 |
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anti-Crk p38 |
|||
| YF-PA23509 | Abfrontier | 50 ul | EUR 334 |
|
Description: Mouse polyclonal to Crk p38 |
|||
 P38 delta protein |
|||
| 30R-2868 | Fitzgerald | 5 ug | EUR 503 |
|
Description: Purified recombinant Human P38 delta protein |
|||
 p38 alpha protein |
|||
| 30R-2870 | Fitzgerald | 5 ug | EUR 503 |
|
Description: Purified recombinant Human p38 alpha protein |
|||
 p38 beta protein |
|||
| 30R-2875 | Fitzgerald | 5 ug | EUR 503 |
|
Description: Purified recombinant Human p38 beta protein |
|||
p38 MAPK antibody |
|||
| 20R-1572 | Fitzgerald | 100 ug | EUR 705 |
|
Description: Rabbit polyclonal p38 MAPK antibody |
|||
P38 MAPK antibody |
|||
| 20R-2087 | Fitzgerald | 50 ug | EUR 281 |
|
Description: Rabbit polyclonal P38 MAPK antibody |
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P38 MAPK antibody |
|||
| 20R-2088 | Fitzgerald | 50 ug | EUR 281 |
|
Description: Rabbit polyclonal P38 MAPK antibody |
|||
P38 MAPK antibody |
|||
| 20R-2403 | Fitzgerald | 50 ug | EUR 281 |
|
Description: Rabbit polyclonal P38 MAPK antibody |
|||
p38 MAPK antibody |
|||
| 20R-2950 | Fitzgerald | 100 ul | EUR 393 |
|
Description: Rabbit polyclonal p38 MAPK antibody |
|||
p38 MAPK antibody |
|||
| 10R-8422 | Fitzgerald | 100 ul | EUR 393 |
|
Description: Mouse monoclonal p38 MAPK antibody |
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 Anti-p38 alpha |
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| DB-1039 | DB Biotech | 100 tests | EUR 474 |
 Anti-p38 beta |
|||
| DB-1040 | DB Biotech | 100 tests | EUR 474 |
 Anti-p38 gamma |
|||
| DB-1041 | DB Biotech | 100 tests | EUR 474 |
 Anti-p38 delta |
|||
| DB-1042 | DB Biotech | 100 tests | EUR 474 |
 Anti-p38-a |
|||
| DB-161-0.05 | DB Biotech | 50 μl | EUR 269 |
Anti-p38-a |
|||
| DB-161-0.1 | DB Biotech | 100 μl | EUR 422 |
 Anti-p38-b |
|||
| DB-162-0.05 | DB Biotech | 50 μl | EUR 269 |
Anti-p38-b |
|||
| DB-162-0.1 | DB Biotech | 100 μl | EUR 422 |
 Anti-p38-g |
|||
| DB-163-0.05 | DB Biotech | 50 μl | EUR 269 |
Anti-p38-g |
|||
| DB-163-0.1 | DB Biotech | 100 μl | EUR 422 |
 Anti-p38-d |
|||
| DB-164-0.05 | DB Biotech | 50 μl | EUR 269 |
Anti-p38-d |
|||
| DB-164-0.1 | DB Biotech | 100 μl | EUR 422 |
Anti-p38 alpha |
|||
| DB1039 | DB Biotech | 100 tests | EUR 474 |
Anti-p38 beta |
|||
| DB1040 | DB Biotech | 100 tests | EUR 474 |
Anti-p38 gamma |
|||
| DB1041 | DB Biotech | 100 tests | EUR 474 |
Anti-p38 delta |
|||
| DB1042 | DB Biotech | 100 tests | EUR 474 |
 anti-p38 MAPK |
|||
| LF-PA0160 | Abfrontier | 100 ul | EUR 334 |
|
Description: Rabbit polyclonal to p38 MAPK |
|||
 Anti-p38 antibody |
|||
| PAab06076 | Lifescience Market | 100 ug | EUR 355 |
 Anti-p38 Antibody |
|||
| A00176 | BosterBio | 100ul | EUR 397 |
|
Description: Rabbit Polyclonal Antibody for p38 Antibody (MAPK14) detection.tested for WB in Human, Mouse, Rat. |
|||
 p38 Polyclonal Antibody |
|||
| ABP57354-003ml | Abbkine | 0.03ml | EUR 158 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38 |
|||
p38 Polyclonal Antibody |
|||
| ABP57354-01ml | Abbkine | 0.1ml | EUR 289 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38 |
|||
p38 Polyclonal Antibody |
|||
| ABP57354-02ml | Abbkine | 0.2ml | EUR 414 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38 |
|||
p38 Polyclonal Antibody |
|||
| ABP52112-003ml | Abbkine | 0.03ml | EUR 158 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182 |
|||
p38 Polyclonal Antibody |
|||
| ABP52112-01ml | Abbkine | 0.1ml | EUR 289 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182 |
|||
p38 Polyclonal Antibody |
|||
| ABP52112-02ml | Abbkine | 0.2ml | EUR 414 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182 |
|||
p38 Polyclonal Antibody |
|||
| ABP52113-003ml | Abbkine | 0.03ml | EUR 158 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323 |
|||
p38 Polyclonal Antibody |
|||
| ABP52113-01ml | Abbkine | 0.1ml | EUR 289 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323 |
|||
p38 Polyclonal Antibody |
|||
| ABP52113-02ml | Abbkine | 0.2ml | EUR 414 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323 |
|||
p38 Polyclonal Antibody |
|||
| ABP53838-003ml | Abbkine | 0.03ml | EUR 158 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180 |
|||
p38 Polyclonal Antibody |
|||
| ABP53838-01ml | Abbkine | 0.1ml | EUR 289 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180 |
|||
p38 Polyclonal Antibody |
|||
| ABP53838-02ml | Abbkine | 0.2ml | EUR 414 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180 |
|||
p38 Polyclonal Antibody |
|||
| ABP53839-003ml | Abbkine | 0.03ml | EUR 158 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182 |
|||
p38 Polyclonal Antibody |
|||
| ABP53839-01ml | Abbkine | 0.1ml | EUR 289 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182 |
|||
p38 Polyclonal Antibody |
|||
| ABP53839-02ml | Abbkine | 0.2ml | EUR 414 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182 |
|||
p38 MAPK Antibody |
|||
| abx236077-100ug | Abbexa | 100 ug | EUR 481 |
 p38 Blocking Peptide |
|||
| 20-abx161932 | Abbexa |
|
|
p38 Blocking Peptide |
|||
| 20-abx061736 | Abbexa |
|
|
p38 Blocking Peptide |
|||
| 20-abx062080 | Abbexa |
|
|
 Antibody) p38 (pY323) Antibody |
|||
| 20-abx133058 | Abbexa |
|
|
 Antibody) p38 (pY182) Antibody |
|||
| 20-abx134951 | Abbexa |
|
|
 Antibody) p38 (pT180) Antibody |
|||
| 20-abx009863 | Abbexa |
|
|
p38 MAPK Antibody |
|||
| 20-abx012798 | Abbexa |
|
|
p38 MAPK Antibody |
|||
| 20-abx012875 | Abbexa |
|
|
 p38 alpha-MAPK14 |
|||
| RA15053 | Neuromics | 100 ug | EUR 526 |
p38 Polyclonal Antibody |
|||
| ES8347-100ul | ELK Biotech | 100ul | EUR 279 |
|
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat/Chicken. This antibody is tested and validated for WB, ELISA, WB, ELISA |
|||
p38 Polyclonal Antibody |
|||
| ES8347-50ul | ELK Biotech | 50ul | EUR 207 |
|
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat/Chicken. This antibody is tested and validated for WB, ELISA, WB, ELISA |
|||
p38 Polyclonal Antibody |
|||
| ES4837-100ul | ELK Biotech | 100ul | EUR 279 |
|
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
|||
p38 Polyclonal Antibody |
|||
| ES4838-100ul | ELK Biotech | 100ul | EUR 279 |
|
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
|||
p38 Polyclonal Antibody |
|||
| ES4838-50ul | ELK Biotech | 50ul | EUR 207 |
|
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
|||
p38 Polyclonal Antibody |
|||
| ES4837-50ul | ELK Biotech | 50ul | EUR 207 |
|
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
|||
p38 Polyclonal Antibody |
|||
| ES3111-50ul | ELK Biotech | 50ul | EUR 207 |
|
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
|||
p38 Polyclonal Antibody |
|||
| ES3112-100ul | ELK Biotech | 100ul | EUR 279 |
|
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
|||
p38 Polyclonal Antibody |
|||
| ES3112-50ul | ELK Biotech | 50ul | EUR 207 |
|
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
|||
p38 Polyclonal Antibody |
|||
| ES3111-100ul | ELK Biotech | 100ul | EUR 279 |
|
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
|||
Anti-p38 antibody |
|||
| STJ97615 | St John's Laboratory | 200 µl | EUR 197 |
|
Description: Rabbit polyclonal to p38. |
|||
Anti-p38 antibody |
|||
| STJ94876 | St John's Laboratory | 200 µl | EUR 197 |
|
Description: Rabbit polyclonal to p38. |
|||
Anti-p38 antibody |
|||
| STJ94877 | St John's Laboratory | 200 µl | EUR 197 |
|
Description: Rabbit polyclonal to p38. |
|||
Anti-p38 antibody |
|||
| STJ94878 | St John's Laboratory | 200 µl | EUR 197 |
|
Description: p38 is a protein encoded by the MAPK14 gene which is approximately 41,2 kDa. p38 is localised to the cytoplasm and nucleus. It is involved in activated TLR4 signalling, the IL-2 pathway, toll-like receptor signalling pathways, the VEGF signalling pathway and 4-1BB pathway. This protein falls under the MAP kinase family. It acts as an integration point for multiple biochemical signals, and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. p38 is expressed in the brain, heart, placenta, pancreas and skeletal muscle. Mutations in the MAPK14 gene may result in patellar tendinitis and lumbosacral lipoma. STJ94878 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of p38 protein. |
|||
Anti-p38 antibody |
|||
| STJ94879 | St John's Laboratory | 200 µl | EUR 197 |
|
Description: Rabbit polyclonal to p38. |
|||
 Anti-P38 antibody |
|||
| STJ98898 | St John's Laboratory | 200 µl | EUR 197 |
|
Description: Mouse monoclonal to P38. |
|||
Anti-P38 antibody |
|||
| STJ98899 | St John's Laboratory | 200 µl | EUR 197 |
|
Description: Mouse monoclonal to P38. |
|||
p38 Polyclonal Antibody |
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| 41305-100ul | SAB | 100ul | EUR 252 |
p38 Polyclonal Antibody |
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| 41305-50ul | SAB | 50ul | EUR 187 |
p38 Polyclonal Antibody |
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| 41306-100ul | SAB | 100ul | EUR 252 |
p38 Polyclonal Antibody |
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| 41306-50ul | SAB | 50ul | EUR 187 |
p38 MAPK Antibody |
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| 49379-100ul | SAB | 100ul | EUR 333 |
p38 MAPK Antibody |
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| 49379-50ul | SAB | 50ul | EUR 239 |
 anti- p38 antibody |
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| FNab06076 | FN Test | 100µg | EUR 505.25 |
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Description: Antibody raised against p38 |
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) Biotin-MBP(94 - 102) |
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| 5-00804 | CHI Scientific | 4 x 5mg | Ask for price |
 Polyclonal SAP 102 Antibody |
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| APR13193G | Leading Biology | 0.05ml | EUR 659 |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human SAP 102 . This antibody is tested and proven to work in the following applications: |
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 HG-10-102-01 |
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| HY-13488 | MedChemExpress | 10mM/1mL | EUR 219 |
 (rat)) CART (55-102) (rat) |
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| B5412-.1 | ApexBio | 100 ug | EUR 502 |
 (human)) CART (55-102) (human) |
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| B5413-.1 | ApexBio | 100 ug | EUR 447 |
HG-10-102-01 |
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| B1262-10 | ApexBio | 10 mg | EUR 303 |
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Description: HG-10-102-01 is a potent and selective inhibitor of leucine-rich repeat kinase 2 (LRRK2) with the IC50 values of 20.3nM and 3.2nM for wild type LRRK2 and LRRK2 [G1019S], respectively [1]. |
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HG-10-102-01 |
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| B1262-25 | ApexBio | 25 mg | EUR 502 |
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Description: HG-10-102-01 is a potent and selective inhibitor of leucine-rich repeat kinase 2 (LRRK2) with the IC50 values of 20.3nM and 3.2nM for wild type LRRK2 and LRRK2 [G1019S], respectively [1]. |
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HG-10-102-01 |
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| B1262-5 | ApexBio | 5 mg | EUR 193 |
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Description: HG-10-102-01 is a potent and selective inhibitor of leucine-rich repeat kinase 2 (LRRK2) with the IC50 values of 20.3nM and 3.2nM for wild type LRRK2 and LRRK2 [G1019S], respectively [1]. |
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HG-10-102-01 |
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| B1262-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 192 |
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Description: HG-10-102-01 is a potent and selective inhibitor of leucine-rich repeat kinase 2 (LRRK2) with the IC50 values of 20.3nM and 3.2nM for wild type LRRK2 and LRRK2 [G1019S], respectively [1]. |
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HG-10-102-01 |
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| B1262-50 | ApexBio | 50 mg | EUR 821 |
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Description: HG-10-102-01 is a potent and selective inhibitor of leucine-rich repeat kinase 2 (LRRK2) with the IC50 values of 20.3nM and 3.2nM for wild type LRRK2 and LRRK2 [G1019S], respectively [1]. |
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CART (55-102) (human) |
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| H-4444.0100 | Bachem | 0.1mg | EUR 393 |
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Description: Sum Formula: C225H365N65O65S7; CAS# [214050-22-3] |
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CART (55-102) (human) |
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| H-4444.0500 | Bachem | 0.5mg | EUR 1482 |
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Description: Sum Formula: C225H365N65O65S7; CAS# [214050-22-3] |
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CART (55-102) (human) |
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| H-4444.1000 | Bachem | 1.0mg | EUR 2207 |
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Description: Sum Formula: C225H365N65O65S7; CAS# [214050-22-3] |
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CART (55-102) (rat) |
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| H-4446.0100 | Bachem | 0.1mg | EUR 393 |
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Description: Sum Formula: C226H367N65O65S7; CAS# [209615-79-2] |
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CART (55-102) (rat) |
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| H-4446.0500 | Bachem | 0.5mg | EUR 1482 |
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Description: Sum Formula: C226H367N65O65S7; CAS# [209615-79-2] |
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CART (55-102) (rat) |
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| H-4446.1000 | Bachem | 1.0mg | EUR 2207 |
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Description: Sum Formula: C226H367N65O65S7; CAS# [209615-79-2] |
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 CLIA Kit) Mouse P38 Mitogen-activated Protein Kinase (MAPK P38) CLIA Kit |
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| abx197397-96tests | Abbexa | 96 tests | EUR 825 |
 ELISA Kit) Mouse MAPK P38(P38 Mitogen-activated Protein Kinase) ELISA Kit |
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| EM1199 | FN Test | 96T | EUR 524.1 |
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Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.75 ng/ml |
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) p38 MAPK antibody (Thr180) |
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| 70R-37313 | Fitzgerald | 100 ug | EUR 349 |
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Description: Rabbit Polyclonal p38 MAPK antibody (Thr180) |
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) p38 MAPK antibody (Tyr182) |
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| 70R-37314 | Fitzgerald | 100 ug | EUR 349 |
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Description: Rabbit Polyclonal p38 MAPK antibody (Tyr182) |
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) p38 MAPK antibody (Tyr322) |
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| 70R-33397 | Fitzgerald | 100 ug | EUR 327 |
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Description: Rabbit polyclonal p38 MAPK antibody (Tyr322) |
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) P38 MAPK antibody (Thr179) |
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| 70R-34324 | Fitzgerald | 100 ug | EUR 327 |
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Description: Rabbit polyclonal P38 MAPK antibody (Thr179) |
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) P38 MAPK antibody (Tyr182) |
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| 70R-34326 | Fitzgerald | 100 ug | EUR 327 |
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Description: Rabbit polyclonal P38 MAPK antibody (Tyr182) |
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 p38 MAPK Blocking Peptide |
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| AF6455-BP | Affbiotech | 1mg | EUR 195 |
p38 MAPK Blocking Peptide |
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| AF6456-BP | Affbiotech | 1mg | EUR 195 |
p38 MAPK Blocking Peptide |
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| AF6457-BP | Affbiotech | 1mg | EUR 195 |
 Antibody) Phospho p38 (Tyr323) Antibody |
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| A1984-100 | Biovision | 100 µl | EUR 379 |
 p38 MAP Kinase antibody |
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| 20R-1458 | Fitzgerald | 100 ug | EUR 673 |
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Description: Rabbit polyclonal p38 MAP Kinase antibody |
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 p38 MAP Kinase Antibody |
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| 3114-100 | Biovision | EUR 343 | |
p38 MAP Kinase Antibody |
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| 3114-30T | Biovision | EUR 146 | |
p38 MAP Kinase antibody |
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| 70R-11620 | Fitzgerald | 100 ug | EUR 418 |
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Description: Rabbit polyclonal p38 MAP Kinase antibody |
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 Phospho-p38 MAPK antibody |
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| 70R-11824 | Fitzgerald | 100 ug | EUR 525 |
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Description: Rabbit polyclonal Phospho-p38 MAPK antibody |
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 Phospho-p38 MAPK Antibody |
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| 3438-100 | Biovision | EUR 425 | |
 p38 gamma/delta Antibody |
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| DF10341 | Affbiotech | 200ul | EUR 304 |
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Description: p38-delta/gamma Antibody detects endogenous levels of p38-delta/gamma. |
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Conclusion: observational, plasma adiponectin and BMI were inversely. In contrast, the high genetic plasma adiponectin is unlikely to affect BMI and high BMI is not possible genetic influences on plasma adiponectin.