A computational guided, functional validation of a novel therapeutic antibody proposes Notch signaling as a clinical relevant and druggable target in glioma

A computational guided, functional validation of a novel therapeutic antibody proposes Notch signaling as a clinical relevant and target in glioma

The Notch signaling network to determine stemness in various tissues and targeting indicates activity on malignant brain cancer by gamma-Secretase inhibitor (GSI) has shown promising preclinical success. However, the translation …

FPIES in exclusively breastfed infants: two case reports and review of the literature

FPIES in exclusively breastfed infants: two case reports and review of the literature

Background: Food Protein-Induced Enterocolitis Syndrome (FPIES) is a non-IgE-mediated food allergy that primarily affects children in the first year of life. Usually the symptoms of ruptured when infant formula or …

Modulatory Role of Reactive Oxygen Species in Root Development in Model Plant of Arabidopsis thaliana

Modulatory Role of Reactive Oxygen Species in Root Development in Model Plant of Arabidopsis thaliana

Reactive oxygen species (ROS), a type of oxygen reduction products monoelectronic, has a high chemical activity of O2. Although ROS pose a potential risk to all organisms through induced oxidative …