Oxidized low-density lipoprotein (oxLDLs) and oxysterols play a key role in the development of endothelial dysfunction and atherosclerosis. Loss of function of vascular endothelium negative impact vasomotion, cell growth, adhesiveness and barrier function. While for some of these disorders plausible explanation can be provided from a mechanistic standpoint, for many others, the molecular players involved are not known. Caveolae, specific plasma membrane domains, has recently emerged as a target and mediator of oxLDL-induced endothelial dysfunction (ED).

Caveolae and their protein Caveolin-1 related (Cav-1) involved in oxLDLs / LDL transcytosis, especially through the scavenger receptor class B type 1 (SR-B1). Instead, oxLDLs LDL receptor endocytosis mediated by lectin-like oxidized 1 (LOX-1), whose activities depend on intact caveolae system. In addition, LOX-1 regulates expression of Cav-1 and vice versa.

 

On the other hand, oxLDLs may affect the plasma membrane cholesterol content / distribution thus affecting the architecture of caveolae, Cav-1 localization and related signals. Overall, this body of evidence shows that caveolae have both active and passive role in oxLDL-induced EC dysfunction. First as a mediator of lipid uptake and transfer in the subendothelial space, and then, as the target of a change in the composition / plasma membrane lipid dynamics resulting from increased levels of circulating oxLDLs.

Getting a better understanding of how oxLDLs interacts with endothelial cells (EC) and caveolae-mediated signaling pathways modulate, leading to ED, it is important to find new targets of intervention to address atherosclerosis and related clinical entities.

Thiol-based switching mechanism of stress-sensing companion

Thiol-based redox switches evolved as post-translational mechanisms that allow for efficient regulation of individual proteins to quickly respond to sudden environmental changes. While some of the functions of proteins need to be turned off to conserve resources and avoid potentially error-prone process, the protective function becomes important and need to be activated. In this review, we focus on the mechanism of thiol-based activation of the stress-sensing chaperones.

After the exposure to stress, the companion converted into a high-affinity binding platform for ongoing proteins and cells to protect against the accumulation of protein aggregates that are potentially toxic. their chaperone activity independent of ATP, a feature that is very important in conditions of oxidative stress, in which cellular ATP levels drop and canonical ATP-dependent chaperone no longer operate.

Likewise, reductive inactivation and release substrates require recovery of ATP levels, which ensures clients with foldases protein folding ATP-dependent. We will provide an overview on the different strategies that cells evolved to rapidly increase an ATP-independent chaperone on oxidative stress and provide mechanistic insight into how stress conditions used to convert the cellular protein overflow into the holding ATP-independent chaperones.

Both lysosomal integral membrane proteins form a complex MFSD1 and GLMP tight that confer protection from both interaction partners against lysosomal proteolysis. We are here enhanced molecular interactions of the two proteins and found that GLMP luminal domain, but not the transmembrane domain or short cytosolic tail, the inherent protection and mediate interactions with MFSD1.Our data support the finding that the interaction is important for the stabilization of the complex.

These results are supplemented by observations that N-glycosylation of GLMP in general, but not the type N-glycans (high-mannose-type or complex-type) or individual N-glycan chains, it is very important for protection. We observed that the interaction of the two proteins has already begun in the endoplasmic reticulum, and quantitative dependent on one another.

Both proteins can affect otherwise their intracellular trafficking to lysosomes in addition to protection from proteolysis. Finally, we provide evidence that can form homodimers MFSD1 both in vitro and in vivo. Our data repair complex interaction between intimate partner of the lysosomal transporter and accessory subunit.

TREND-DB-atlas transcriptome-wide dynamic landscape of alternative polyadenylation

alternative polyadenylation (APA) extend deep transcriptome complexity. Disruption of the APA can interfere with biological processes, ultimately resulting in disruption destroy. The main challenge in identifying the mechanisms and consequences of APA (and its disturbances) lies in the complexity of the RNA 3 ‘end processing, which involves poorly conserved RNA motif and multi-component complex consisting of more than 50 proteins.

It is more complicated that the RNA 3 ‘end maturation closely associated with transcription, RNA processing and even epigenetic (histone / DNA / RNA) modification. Here, we present TREND-DB , resource cataloging dynamic landscape APA after depletion> 170 proteins involved in various aspects of transcription, gene regulation co- and post-transcriptional, and epigenetic modifications further processing. TREND-DB visualization transcriptome dynamics 3 ‘diversification end (TREND) in a very interactive; APA provides global network maps and allows interrogating genes influenced by APA-specific regulator and vice versa. It also allows the analysis of functional enrichment of specific conditions WHAT affected genes, which show wide biological and clinical relevance in all conditions of RNAi.

DFS-"HOT" Taq DNA Polymerase (DNA-free sensitive, E-coli. DNA Free)
N152	GeneOn	5x500 units	EUR 472.8

DFS-"HOT" Taq DNA Polymerase (DNA-free sensitive, E-coli. DNA Free)
N154	GeneOn	20x500 units	EUR 1830

DNA Ligase I (DNA Ligase I) Antibody
abx232431-100ug	Abbexa	100 ug	EUR 577.2

T4 DNA Ligase T4 DNA Ligase catalyses
MBT091-5000U	EWC Diagnostics	1 unit	EUR 167.61
Description: T4 DNA Ligase T4 DNA Ligase catalyses

T7 DNA
310-005	GeneOn	200µg	EUR 98.4

T7 DNA
310-025	GeneOn	5x200 µg	EUR 270

ds DNA
1107NF-B412	Antagene	0.2mg	EUR 180

T4 DNA
enz-286	ProSpec Tany	20,000IU	EUR 65
Description: Recombinant T4 DNA Ligase

DNA, ds
MBS6507401-05mL	MyBiosource	0.5mL	EUR 760

DNA, ds
MBS6507401-5x05mL	MyBiosource	5x0.5mL	EUR 3270

DNA, ds
MBS6507402-01mg	MyBiosource	0.1mg	EUR 765

DNA, ds
MBS6507402-5x01mg	MyBiosource	5x0.1mg	EUR 3300

DNA, ss
MBS6507403-005mg	MyBiosource	0.05mg	EUR 855

DNA, ss
MBS6507403-5x005mg	MyBiosource	5x0.05mg	EUR 3705

DNA pol
ABF9055	Lifescience Market	100 ug	EUR 525.6

DNA PKcs
E8ET1610-12	EnoGene	100ul	EUR 275
Description: Available in various conjugation types.

DNA STAT
TL-4210	Tel-Test	100ml	EUR 158

DNA STAT
TL-4220	Tel-Test	200ml	EUR 276

DNA PKcs
MBS8533923-01mL	MyBiosource	0.1mL	EUR 345

DNA PKcs
MBS8533923-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 565

DNA PKcs
MBS8533923-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 565

DNA PKcs
MBS8533923-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 565

DNA PKcs
MBS8533923-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 565

pUC18 DNA
G40-300	GeneOn	50µg	EUR 67.2

pUC18 DNA
G40-305	GeneOn	5x50µg	EUR 176.4

Taq DNA polymerase (TQ21) , DNA Aptamer, unlabeled
AD-146-U	Alpha Diagnostics	Custom	Ask for price

DNA-Fect
DF37100-1	Neuromics	1 ml	EUR 418.8

Lambda DNA
67291	Sisco Laboratories	100 mcg	EUR 35.92
Description: Part E

Lambda DNA
67291-1	Sisco Laboratories	250 mcg	EUR 85.53
Description: Part E

pBR322 DNA
MSD14	Bio Basic	50ug	EUR 183.19

Lambda DNA
PCR-259	Jena Bioscience GmbH	2 x 1ml	EUR 59.1

DNA-Fect
MBS556500-1mL	MyBiosource	1mL	EUR 350

DNA-Fect
MBS556500-5x1mL	MyBiosource	5x1mL	EUR 1420

DiscoveryProbe™ DNA Damage/DNA Repair Library
L1033-.096	ApexBio	100uL/well(10 mM solution),96 Well Deep Well Plate	EUR 5584
Description: A unique collection of 481 DNA Damage/DNA repair-related compounds for DNA damage/DNA repair research.

DiscoveryProbe™ DNA Damage/DNA Repair Library
L1033-.1	ApexBio	100 uL/well(10 mM solution)	EUR 6976
Description: A unique collection of 481 DNA Damage/DNA repair-related compounds for DNA damage/DNA repair research.

DiscoveryProbe™ DNA Damage/DNA Repair Library
L1033-.25	ApexBio	250 uL/well(10 mM solution)	EUR 12464
Description: A unique collection of 481 DNA Damage/DNA repair-related compounds for DNA damage/DNA repair research.

DNA Primase
E8ER1907-59	EnoGene	100ul	EUR 275
Description: Available in various conjugation types.

DNA Primase
MBS8577452-01mL	MyBiosource	0.1mL	EUR 345

DNA Primase
MBS8577452-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 565

DNA Primase
MBS8577452-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 565

DNA Primase
MBS8577452-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 565

DNA Primase
MBS8577452-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 565

Taq DNA polymerase (TQ21) , DNA Aptamer, Biotinylated
AD-146-B	Alpha Diagnostics	Custom	Ask for price

DNA Antibody
abx023805-02mg	Abbexa	0.2 mg	EUR 777.6

DNA antibody
10-D20A	Fitzgerald	500 ug	EUR 399
Description: Mouse monoclonal DNA antibody

DNA antibody
10R-D114b	Fitzgerald	100 ug	EUR 517
Description: Mouse monoclonal DNA antibody

DNA antibody
10C-CR6034M1	Fitzgerald	100 ug	EUR 95
Description: Mouse monoclonal DNA antibody

DNA, Antibody
GWB-29C3BF	GenWay Biotech	1 mg	Ask for price

DNA Antibody
GWB-Q01107	GenWay Biotech	0.1 mg	Ask for price

DNA Antibody
GWB-7F5457	GenWay Biotech	0.2 mg	Ask for price

DNA, Antibody
GWB-76482C	GenWay Biotech	0.1 mg	Ask for price

DNA, Antibody
GWB-FA8229	GenWay Biotech	1 mg	Ask for price

DNA, Antibody
GWB-B2ACF7	GenWay Biotech	0.1 mg	Ask for price

DNA Antibody
GWB-BA4954	GenWay Biotech	0.05 mg	Ask for price

DNA antibody
MBS531598-01mg	MyBiosource	0.1mg	EUR 525

DNA antibody
MBS531598-5x01mg	MyBiosource	5x0.1mg	EUR 2220

DNA antibody
MBS530500-05mg	MyBiosource	0.5mg	EUR 980

DNA antibody
MBS530500-5x05mg	MyBiosource	5x0.5mg	EUR 4255

DNA antibody
MBS530645-01mg	MyBiosource	0.1mg	EUR 845

DNA antibody
MBS530645-5x01mg	MyBiosource	5x0.1mg	EUR 3650

DNA-Fect293
DF37293-1	Neuromics	1 ml	EUR 349.2

Activated DNA
80605	BPS Bioscience	500 µL	EUR 125
Description: Activated DNA for PARP assay, for use with BPS's assay kits for PARPs 1, 2, 3, and 6. PARP1 Chemiluminescent Assay Kit, #80551 ; PARP2 Chemiluminescent Assay Kit, #80552; PARP3 Chemiluminescent Assay Kit, #80553; PARP6 Chemiluminescent Assay Kit, #80556; PARP2 Homogeneous Assay Kit, #80702

DNA-Fect293
MBS556501-1mL	MyBiosource	1mL	EUR 305

DNA-Fect293
MBS556501-5x1mL	MyBiosource	5x1mL	EUR 1220

DNA Polymerase
ABF5235	Lifescience Market	100 ug	EUR 525.6

DNA Polymerase
ABD3082	Lifescience Market	100 ug	EUR 525.6

DNA Polymerase
abx461001-1096tests	Abbexa	10 × 96 tests	Ask for price

DNA Polymerase
abx461001-596tests	Abbexa	5 × 96 tests	Ask for price

DNA Polymerase
abx461001-96tests	Abbexa	96 tests	EUR 425

DNA-fectamine
DNAF001	Bio Basic	1ml	EUR 334.57

DNA Quantitation
LO202551	Westburg	each	Ask for price

DNA-Spermidine
T31554-10mg	TargetMol Chemicals	10mg	Ask for price
Description: DNA-Spermidine

DNA-Spermidine
T31554-1g	TargetMol Chemicals	1g	Ask for price
Description: DNA-Spermidine

DNA-Spermidine
T31554-1mg	TargetMol Chemicals	1mg	Ask for price
Description: DNA-Spermidine

DNA-Spermidine
T31554-50mg	TargetMol Chemicals	50mg	Ask for price
Description: DNA-Spermidine

DNA-Spermidine
T31554-5mg	TargetMol Chemicals	5mg	Ask for price
Description: DNA-Spermidine

DNA, Intercolated
MBS603098-02mg	MyBiosource	0.2mg	EUR 580

DNA, Intercolated
MBS603098-5x02mg	MyBiosource	5x0.2mg	EUR 2470

DNA-Spermidine
MBS5781157-5mg	MyBiosource	5(mg	EUR 915

DNA-Spermidine
MBS5781157-5x5mg	MyBiosource	5x5(mg	EUR 3970

Recombinant Monkeypox Virus DNA-directed DNA polymerase
MPXV-0438	Creative BioMart	100ug	EUR 3198.4
Description: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa)
MBS648582-02mL	MyBiosource	0.2mL	EUR 695

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa)
MBS648582-5x02mL	MyBiosource	5x0.2mL	EUR 2975

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (1mg Relaxed DNA + 2000u Gyrase)
TG2000G-7KIT	TopoGen	2000 assays	EUR 3412.8

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (500ug Relaxed DNA + 1000u Gyrase)
TG2000G-5KIT	TopoGen	1000 assays	EUR 1934.4

Taq Plus DNA Polymerase (Taq Plus DNA) Protein
abx073522-100tests	Abbexa	100 tests	EUR 225

Human DNA-directed DNA/RNA polymerase mu (POLM)
1-CSB-YP889065HU	Cusabio	Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Human DNA-directed DNA/RNA polymerase mu(POLM) expressed in Yeast

Human DNA-directed DNA/RNA polymerase mu (POLM)
1-CSB-BP889065HU	Cusabio	Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Human DNA-directed DNA/RNA polymerase mu(POLM) expressed in Baculovirus

Human DNA-directed DNA/RNA polymerase mu (POLM)
1-CSB-EP889065HU	Cusabio	Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Human DNA-directed DNA/RNA polymerase mu(POLM) expressed in E.coli

Maximo DFS-Plus Taq DNA Polymerase DNA-free
N140	GeneOn	500 units	EUR 60

Maximo DFS-Plus Taq DNA Polymerase DNA-free
N142	GeneOn	5x500 units	EUR 144

Maximo DFS-Plus Taq DNA Polymerase DNA-free
N144	GeneOn	20x500 units	EUR 440.4

Taq DNA polymerase (TQ21) , DNA Aptamer, FITC labeled
AD-146-F	Alpha Diagnostics	Custom	Ask for price

DNA Advanced DNA Clean Up and Concentrator System
DC1001	Viogene	50 preps	EUR 104.58

DNA Advanced DNA Clean Up and Concentrator System
DC1002	Viogene	250 preps	EUR 427.48

POLQ (DNA Polymerase theta, DNA Polymerase eta, POLH)
MBS6008714-01mg	MyBiosource	0.1(mg	EUR 520

POLQ (DNA Polymerase theta, DNA Polymerase eta, POLH)
MBS6008714-5x01mg	MyBiosource	5x0.1mg	EUR 2185

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (50ug Relaxed DNA + 100u Gyrase)
TG2000G-1KIT	TopoGen	100 assays	EUR 456

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (250ug Relaxed DNA + 500u Gyrase)
TG2000G-3KIT	TopoGen	500 assays	EUR 1182

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (AP)
MBS6335631-02mL	MyBiosource	0.2mL	EUR 980

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (AP)
MBS6335631-5x02mL	MyBiosource	5x0.2mL	EUR 4250

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (PE)
MBS6335641-02mL	MyBiosource	0.2mL	EUR 980

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (PE)
MBS6335641-5x02mL	MyBiosource	5x0.2mL	EUR 4250

DNA Amplification Kit with Taq DNA Polymerase, 100app
PL1202-K	Vivantis	each	Ask for price

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (APC)
MBS6335632-02mL	MyBiosource	0.2mL	EUR 980

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (APC)
MBS6335632-5x02mL	MyBiosource	5x0.2mL	EUR 4250

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (FITC)
MBS6335634-02mL	MyBiosource	0.2mL	EUR 980

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (FITC)
MBS6335634-5x02mL	MyBiosource	5x0.2mL	EUR 4250

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (HRP)
MBS6335635-02mL	MyBiosource	0.2mL	EUR 980

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (HRP)
MBS6335635-5x02mL	MyBiosource	5x0.2mL	EUR 4250

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (Biotin)
MBS6335633-02mL	MyBiosource	0.2mL	EUR 980

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (Biotin)
MBS6335633-5x02mL	MyBiosource	5x0.2mL	EUR 4250

Human Neutrophil Elastase (DNA I) , DNA Aptamer, unlabeled
AD-155-U	Alpha Diagnostics	Custom	Ask for price

Recombinant human DNA-directed DNA/RNA polymerase mu
P2815	FN Test	100ug	Ask for price
Description: Recombinant protein for human DNA-directed DNA/RNA polymerase mu

DNA nucleotidylexotransferase
AP88338	SAB	1mg	EUR 2640

DNA nucleotidylexotransferase
AP88424	SAB	1mg	EUR 2640

DNA PK, Catalytic Subunit (DNA-dependent Protein Kinase)
MBS611495-005mg	MyBiosource	0.05mg	EUR 810

DNA PK, Catalytic Subunit (DNA-dependent Protein Kinase)
MBS611495-5x005mg	MyBiosource	5x0.05mg	EUR 3490

DNA PK, Catalytic Subunit (DNA-dependent Protein Kinase)
MBS611029-01mg	MyBiosource	0.1mg	EUR 490

DNA PK, Catalytic Subunit (DNA-dependent Protein Kinase)
MBS611029-5x01mg	MyBiosource	5x0.1mg	EUR 2055

DNA PK, Catalytic Subunit (DNA-dependent Protein Kinase)
MBS603492-05mL	MyBiosource	0.5mL	EUR 780

DNA PK, Catalytic Subunit (DNA-dependent Protein Kinase)
MBS603492-5x05mL	MyBiosource	5x0.5mL	EUR 3365

DNA PK, Catalytic Subunit (DNA-dependent Protein Kinase)
MBS614809-01mL	MyBiosource	0.1mL	EUR 860

DNA PK, Catalytic Subunit (DNA-dependent Protein Kinase)
MBS614809-5x01mL	MyBiosource	5x0.1mL	EUR 3725

Human Neutrophil Elastase (DNA I) , DNA Aptamer, Biotinylated
AD-155-B	Alpha Diagnostics	Custom	Ask for price

Anti-DNA Primase, p49 (DNA Primase Small Subunit, DNA Primase 49kD Subunit, Prim1)
MBS626910-01mL	MyBiosource	0.1mL	EUR 825

Anti-DNA Primase, p49 (DNA Primase Small Subunit, DNA Primase 49kD Subunit, Prim1)
MBS626910-5x01mL	MyBiosource	5x0.1mL	EUR 3560

Mouse Anti-DNA Antibody (DNA) ELISA Kit
abx257816-96tests	Abbexa	96 tests	EUR 895.2

DiscoveryProbe? DNA Damage/DNA Repair-related Compounds Panel
L1007-5	ApexBio	5 mg/well	EUR 7172.4
Description: A wide range of well-characterized bioactive molecules that covers various targets related to DNA damage/DNA repair, including ATM/ATR, HDAC, and topoisomerase etc. Facilitate your research towards the insights of cancer, genome instability and immune diseases etc.

Recombinant Monkeypox Virus Protein, DNA-directed DNA polymerase
MPXV-0706	Creative BioMart	100ug	EUR 3198.4
Description: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.

DNA, ss,ds
MBS606065-05mg	MyBiosource	0.5mg	EUR 1285

DNA, ss,ds
MBS606065-5x05mg	MyBiosource	5x0.5mg	EUR 5640

DNA, ds (AP)
MBS6241662-01mL	MyBiosource	0.1(mL	EUR 1055

DNA, ds (AP)
MBS6241662-5x01mL	MyBiosource	5x0.1mL	EUR 4600

DNA, ds (PE)
MBS6244326-01mL	MyBiosource	0.1(mL	EUR 1055

DNA, ds (PE)
MBS6244326-5x01mL	MyBiosource	5x0.1mL	EUR 4600

pUC 18 DNA
MSD15	Bio Basic	50ug	EUR 146.65

pUC 19 DNA
MSD16	Bio Basic	50ug	EUR 136.21

pUC 57 DNA
MSD17	Bio Basic	50ug	EUR 136.21

MAb to DNA
MBS311016-1mg	MyBiosource	1mg	EUR 1905

MAb to DNA
MBS311016-5x1mg	MyBiosource	5x1mg	EUR 8390

DNA, ds (HRP)
MBS6243793-01mL	MyBiosource	0.1(mL	EUR 1055

DNA, ds (HRP)
MBS6243793-5x01mL	MyBiosource	5x0.1mL	EUR 4600

DNA, ds (APC)
MBS6242195-01mL	MyBiosource	0.1(mL	EUR 1055

DNA, ds (APC)
MBS6242195-5x01mL	MyBiosource	5x0.1mL	EUR 4600

DNA Methyltransferase 1, phosphorylated (Ser714) (Dnmt 1, MCMT, M.Hsa1, DNA cytosine 5 methyltransferase 1, DNA MTase Mmu1, DNA methyltransferase M.HsaI)
MBS629513-04mL	MyBiosource	0.4mL	EUR 870

DNA Methyltransferase 1, phosphorylated (Ser714) (Dnmt 1, MCMT, M.Hsa1, DNA cytosine 5 methyltransferase 1, DNA MTase Mmu1, DNA methyltransferase M.HsaI)
MBS629513-5x04mL	MyBiosource	5x0.4mL	EUR 3765

DNA, ds (FITC)
MBS6243260-01mL	MyBiosource	0.1(mL	EUR 1055

DNA, ds (FITC)
MBS6243260-5x01mL	MyBiosource	5x0.1mL	EUR 4600

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (MaxLight 405)
MBS6335636-01mL	MyBiosource	0.1mL	EUR 980

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (MaxLight 405)
MBS6335636-5x01mL	MyBiosource	5x0.1mL	EUR 4250

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (MaxLight 490)
MBS6335637-01mL	MyBiosource	0.1mL	EUR 980

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (MaxLight 490)
MBS6335637-5x01mL	MyBiosource	5x0.1mL	EUR 4250

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (MaxLight 550)
MBS6335638-01mL	MyBiosource	0.1mL	EUR 980

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (MaxLight 550)
MBS6335638-5x01mL	MyBiosource	5x0.1mL	EUR 4250

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (MaxLight 650)
MBS6335639-01mL	MyBiosource	0.1mL	EUR 980

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (MaxLight 650)
MBS6335639-5x01mL	MyBiosource	5x0.1mL	EUR 4250

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (MaxLight 750)
MBS6335640-01mL	MyBiosource	0.1mL	EUR 980

POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa) (MaxLight 750)
MBS6335640-5x01mL	MyBiosource	5x0.1mL	EUR 4250

Soil DNA Kit
AGDK-0016	AcceGen	Kit	Ask for price
Description: Soil DNA Kit offers a rapid and easy-to-use method for the isolation of microbial genomic DNA from all soil samples. This kit is based on spin column chromatography as the separation matrix. After cell lysis, the DNA purification process can be completed in fewer than 20 minutes. The purified DNA is fully digestible with all restriction enzymes tested, and is completely compatible with downstream application such as PCR, qPCR, genotyping, sequencing, Southern Blot analysis, and more.

Soil DNA Kit
AGDK-0035	AcceGen	Kit	Ask for price
Description: Soil DNA Kit is designed for isolation of high quality DNA from from soil samples. The kit utilizes our unique high-capacity magnetic bead technology that ensures efficient recovery of DNA fragment library within a desired fragment length range. After cell lysis, the DNA purification process can be completed in fewer than 20 minutes. The purified DNA is completely compatible with downstream application such as PCR, qPCR, genotyping, sequencing, Southern Blot analysis, and more. The system allows for automation after sample lysis via Hamilton STAR™, Thermo KingFisher™ Flex, Applied Biosystems® MagMAX™, Qiagen Biosprint, and other liquid handling instruments.

DNA Pure Kit
FYG601-100P	Yeastern Biotech	100 Preps	Ask for price

DNA Pure Kit
FYG601-300P	Yeastern Biotech	300 Preps	Ask for price

Taq Plus DNA
enz-309	ProSpec Tany	250U	EUR 60
Description: Recombinant Taq Plus DNA Polymerase

Anti-DNA Antibody (DNA11)
MBS1568812-01mg	MyBiosource	0.1mg	EUR 405

Anti-DNA Antibody (DNA11)
MBS1568812-5x01mg	MyBiosource	5x0.1mg	EUR 1520

Anti-DNA Antibody (DNA12)
MBS1568813-01mg	MyBiosource	0.1mg	EUR 405

Anti-DNA Antibody (DNA12)
MBS1568813-5x01mg	MyBiosource	5x0.1mg	EUR 1520

Anti-DNA Antibody (DNA13)
MBS1568814-01mg	MyBiosource	0.1mg	EUR 405

Anti-DNA Antibody (DNA13)
MBS1568814-5x01mg	MyBiosource	5x0.1mg	EUR 1520

2K DNA Marker
20-abx098045	Abbexa	Ask for price Ask for price	2.5 ml 500 ul

5K DNA Marker
20-abx098048	Abbexa	Ask for price Ask for price	2.5 ml 500 ul

T4 DNA Ligase
abx098136-10kU	Abbexa	10 kU	EUR 385.2

T4 DNA Ligase
abx098136-20Ku	Abbexa	20 Ku	EUR 477.6

DNA Assay Kit
6023	Chondrex	1 kit	EUR 113
Description: Tissue Extract, Cultured Cells

Phage λ-DNA
301-025	GeneOn	500 µg	EUR 122.4

Phage λ-DNA
301-100	GeneOn	5x500µg	EUR 426

T4 DNA ligase
402-002	GeneOn	400 WEISS UNITS	EUR 75.6

T4 DNA ligase
402-010	GeneOn	2000 WEISS UNITS	EUR 184.8

DNA Ligase IV
E8ET1705-77	EnoGene	100ul	EUR 275
Description: Available in various conjugation types.

DNA Ligase I
E8ET7107-14	EnoGene	100ul	EUR 275
Description: Available in various conjugation types.

DNA ligase 1
AP82345	SAB	1mg	EUR 2640

DNA ligase 3
AP82579	SAB	1mg	EUR 2640

DNA ligase 3
AP82720	SAB	1mg	EUR 2640

DNA ligase 1
AP82852	SAB	1mg	EUR 2640

DNA ligase 1
AP83036	SAB	1mg	EUR 2640

T4 DNA Ligase
C301-01	Vazyme	40,000 U	EUR 29

Viral DNA Kit
AGDK-0010	AcceGen	Kit	Ask for price
Description: Viral DNA Kit offers a rapid and easy-to-use method for the isolation of high quality virus DNA from 1-200ul serum, plasma, and cell-free medium. This kit is based on spin column chromatography as the separation matrix. The purified DNA is fully digestible with all restriction enzymes tested, and is completely compatible with downstream application such as PCR, qPCR, genotyping, sequencing, Southern Blot analysis, and more.

Plant DNA Kit
AGDK-0011	AcceGen	Kit	Ask for price
Description: Plant DNA Kit is designed for isolation of high quality DNA from from a wide variety of plant species. Up to 100 mg of wet samples or 30 mg dry samples can be processed in less than 30 minutes.This kit is based on spin column chromatography as the separation matrix. This kit uses a novel and proprietary method to eliminate polysaccharides, phenolic compounds, and enzyme inhibitors from plant sample.The purified DNA is fully digestible with all restriction enzymes tested, and is completely compatible with downstream application such as PCR, qPCR, genotyping, sequencing, Southern Blot analysis, and more.

Plant DNA Kit
AGDK-0028	AcceGen	Kit	Ask for price
Description: Plant DNA Kit is designed for isolation of high quality DNA from from a wide variety of plant species. Up to 100 mg of wet samples or 30 mg dry samples can be processed in less than 30 minutes. The kit utilizes our unique high-capacity magnetic bead technology that ensures efficient recovery of DNA fragment library within a desired fragment length range. The purified DNA is completely compatible with downstream application such as PCR, qPCR, genotyping, sequencing, Southern Blot analysis, and more.

DNA Assay Kit
Z5030023	Biochain	250 assays	EUR 636

T4 DNA ligase
MBT091-10000U	EWC Diagnostics	1 unit	EUR 239.21
Description: T4 DNA ligase

T4 DNA ligase
MBT091-1000U	EWC Diagnostics	1 unit	EUR 37.28
Description: T4 DNA ligase

T4 DNA ligase
CMC12	Creative BioMart	1000U	EUR 558.4
Description: T4 DNA ligase in 10mM Tris-HCl, 50mM KCl, 1mM dithiothreitol, 0.1mM EDTA, 0.2 mg/ml BSA, 50% glycerol, pH 7.4 (25℃) should be stored at -20-deg-C.

Human COT DNA
E4110-01	EURx	0.5mg	EUR 114.45
Description: Human placenta COT DNA optimized for a size range of 50 to 300 bp

Human COT DNA
E4110-02	EURx	2mg	EUR 431.64
Description: Human placenta COT DNA optimized for a size range of 50 to 300 bp

T4 DNA Ligase
G467	ABM	200 U (200 μl)	EUR 60
Description: T4 DNA Ligase catalyzes the formation of a phosphodiester bond between the proximal 3’- hydroxyl and 5’- phosphate ends of adjacent, nicked nucleotides of dsDNA, dsRNA or DNA-RNA hybrids. Known to proceed via an adenylated intermediate, this endergonic reaction can be utilized to join both cohesive-ended and blunt-ended termini.

T4 DNA Ligase
EN-149L	Jena Bioscience GmbH	5 x 400Weiss units	EUR 149.7
Description: E. coli lambda lysogen NM 989

T4 DNA Ligase
EN-149S	Jena Bioscience GmbH	400Weiss units	EUR 37.6
Description: E. coli lambda lysogen NM 989

T4 DNA Ligase
N103-01	Vazyme	600,000 U	EUR 468

Implementation of the UCSC Genome Browser provides additional customized layer of gene regulation accounting for individual transcript isoforms (eg, epigenetic, miRNA-binding sites and RNA-binding protein). TREND-DB that encourages APA outlines roles for various biological program, including potential disease mechanisms, and help identify potential diagnostic and therapeutic them.