Oxidized low-density lipoprotein (oxLDLs) and oxysterols play a key role in the development of endothelial dysfunction and atherosclerosis. Loss of function of vascular endothelium negative impact vasomotion, cell growth, adhesiveness and barrier function. While for some of these disorders plausible explanation can be provided from a mechanistic standpoint, for many others, the molecular players involved are not known. Caveolae, specific plasma membrane domains, has recently emerged as a target and mediator of oxLDL-induced endothelial dysfunction (ED).
Caveolae and their protein Caveolin-1 related (Cav-1) involved in oxLDLs / LDL transcytosis, especially through the scavenger receptor class B type 1 (SR-B1). Instead, oxLDLs LDL receptor endocytosis mediated by lectin-like oxidized 1 (LOX-1), whose activities depend on intact caveolae system. In addition, LOX-1 regulates expression of Cav-1 and vice versa.
On the other hand, oxLDLs may affect the plasma membrane cholesterol content / distribution thus affecting the architecture of caveolae, Cav-1 localization and related signals. Overall, this body of evidence shows that caveolae have both active and passive role in oxLDL-induced EC dysfunction. First as a mediator of lipid uptake and transfer in the subendothelial space, and then, as the target of a change in the composition / plasma membrane lipid dynamics resulting from increased levels of circulating oxLDLs.
Getting a better understanding of how oxLDLs interacts with endothelial cells (EC) and caveolae-mediated signaling pathways modulate, leading to ED, it is important to find new targets of intervention to address atherosclerosis and related clinical entities.
Thiol-based switching mechanism of stress-sensing companion
Thiol-based redox switches evolved as post-translational mechanisms that allow for efficient regulation of individual proteins to quickly respond to sudden environmental changes. While some of the functions of proteins need to be turned off to conserve resources and avoid potentially error-prone process, the protective function becomes important and need to be activated. In this review, we focus on the mechanism of thiol-based activation of the stress-sensing chaperones.
After the exposure to stress, the companion converted into a high-affinity binding platform for ongoing proteins and cells to protect against the accumulation of protein aggregates that are potentially toxic. their chaperone activity independent of ATP, a feature that is very important in conditions of oxidative stress, in which cellular ATP levels drop and canonical ATP-dependent chaperone no longer operate.
Likewise, reductive inactivation and release substrates require recovery of ATP levels, which ensures clients with foldases protein folding ATP-dependent. We will provide an overview on the different strategies that cells evolved to rapidly increase an ATP-independent chaperone on oxidative stress and provide mechanistic insight into how stress conditions used to convert the cellular protein overflow into the holding ATP-independent chaperones.
Both lysosomal integral membrane proteins form a complex MFSD1 and GLMP tight that confer protection from both interaction partners against lysosomal proteolysis. We are here enhanced molecular interactions of the two proteins and found that GLMP luminal domain, but not the transmembrane domain or short cytosolic tail, the inherent protection and mediate interactions with MFSD1.Our data support the finding that the interaction is important for the stabilization of the complex.
These results are supplemented by observations that N-glycosylation of GLMP in general, but not the type N-glycans (high-mannose-type or complex-type) or individual N-glycan chains, it is very important for protection. We observed that the interaction of the two proteins has already begun in the endoplasmic reticulum, and quantitative dependent on one another.
Both proteins can affect otherwise their intracellular trafficking to lysosomes in addition to protection from proteolysis. Finally, we provide evidence that can form homodimers MFSD1 both in vitro and in vivo. Our data repair complex interaction between intimate partner of the lysosomal transporter and accessory subunit.

TREND-DB-atlas transcriptome-wide dynamic landscape of alternative polyadenylation
alternative polyadenylation (APA) extend deep transcriptome complexity. Disruption of the APA can interfere with biological processes, ultimately resulting in disruption destroy. The main challenge in identifying the mechanisms and consequences of APA (and its disturbances) lies in the complexity of the RNA 3 ‘end processing, which involves poorly conserved RNA motif and multi-component complex consisting of more than 50 proteins.
It is more complicated that the RNA 3 ‘end maturation closely associated with transcription, RNA processing and even epigenetic (histone / DNA / RNA) modification. Here, we present TREND-DB , resource cataloging dynamic landscape APA after depletion> 170 proteins involved in various aspects of transcription, gene regulation co- and post-transcriptional, and epigenetic modifications further processing. TREND-DB visualization transcriptome dynamics 3 ‘diversification end (TREND) in a very interactive; APA provides global network maps and allows interrogating genes influenced by APA-specific regulator and vice versa. It also allows the analysis of functional enrichment of specific conditions WHAT affected genes, which show wide biological and clinical relevance in all conditions of RNAi.
pUC18 DNA |
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G40-300 | GeneOn | 50µg | EUR 67.2 |
pUC18 DNA |
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G40-305 | GeneOn | 5x50µg | EUR 176.4 |
DNA-Fect |
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DF37100-1 | Neuromics | 1 ml | EUR 418.8 |
pBR322 DNA |
|||
MSD14 | Bio Basic | 50ug | EUR 183.19 |
DNA Primase |
|||
E8ER1907-59 | EnoGene | 100ul | EUR 275 |
Description: Available in various conjugation types. |
DNA Ligase I (DNA Ligase I) Antibody |
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abx232431-100ug | Abbexa | 100 ug | EUR 577.2 |
DNA antibody |
|||
10-D20A | Fitzgerald | 500 ug | EUR 591.6 |
Description: Mouse monoclonal DNA antibody |
DNA antibody |
|||
10C-CR6034M1 | Fitzgerald | 100 ug | EUR 289.2 |
Description: Mouse monoclonal DNA antibody |
DNA antibody |
|||
10R-D114b | Fitzgerald | 100 ug | EUR 672 |
Description: Mouse monoclonal DNA antibody |
DNA Antibody |
|||
abx023805-02mg | Abbexa | 0.2 mg | EUR 777.6 |
DFS-"HOT" Taq DNA Polymerase (DNA-free sensitive, E-coli. DNA Free) |
|||
N150 | GeneOn | 500 units | EUR 122.4 |
DFS-"HOT" Taq DNA Polymerase (DNA-free sensitive, E-coli. DNA Free) |
|||
N152 | GeneOn | 5x500 units | EUR 472.8 |
DFS-"HOT" Taq DNA Polymerase (DNA-free sensitive, E-coli. DNA Free) |
|||
N154 | GeneOn | 20x500 units | EUR 1830 |
Activated DNA |
|||
80605 | BPS Bioscience | 500 µL | EUR 125 |
Description: Activated DNA for PARP assay, for use with BPS's assay kits for PARPs 1, 2, 3, and 6. PARP1 Chemiluminescent Assay Kit, #80551 ; PARP2 Chemiluminescent Assay Kit, #80552; PARP3 Chemiluminescent Assay Kit, #80553; PARP6 Chemiluminescent Assay Kit, #80556; PARP2 Homogeneous Assay Kit, #80702 |
DNA-Fect293 |
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DF37293-1 | Neuromics | 1 ml | EUR 349.2 |
DNA Polymerase |
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ABD3082 | Lifescience Market | 100 ug | EUR 525.6 |
DNA Polymerase |
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ABF5235 | Lifescience Market | 100 ug | EUR 525.6 |
DNA-fectamine |
|||
DNAF001 | Bio Basic | 1ml | EUR 334.57 |
Taq DNA polymerase (TQ21) , DNA Aptamer, unlabeled |
|||
AD-146-U | Alpha Diagnostics | Custom | Ask for price |
DiscoveryProbe™ DNA Damage/DNA Repair Library |
|||
L1033-.096 | ApexBio | 100uL/well(10 mM solution),96 Well Deep Well Plate | EUR 6980 |
Description: A unique collection of 481 DNA Damage/DNA repair-related compounds for DNA damage/DNA repair research. |
Taq DNA polymerase (TQ21) , DNA Aptamer, Biotinylated |
|||
AD-146-B | Alpha Diagnostics | Custom | Ask for price |
Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (1mg Relaxed DNA + 2000u Gyrase) |
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TG2000G-7KIT | TopoGen | 2000 assays | EUR 3412.8 |
Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (500ug Relaxed DNA + 1000u Gyrase) |
|||
TG2000G-5KIT | TopoGen | 1000 assays | EUR 1934.4 |
Human DNA-directed DNA/RNA polymerase mu (POLM) |
|||
1-CSB-BP889065HU | Cusabio |
|
|
Description: Recombinant Human DNA-directed DNA/RNA polymerase mu(POLM) expressed in Baculovirus |
Human DNA-directed DNA/RNA polymerase mu (POLM) |
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1-CSB-YP889065HU | Cusabio |
|
|
Description: Recombinant Human DNA-directed DNA/RNA polymerase mu(POLM) expressed in Yeast |
Human DNA-directed DNA/RNA polymerase mu (POLM) |
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1-CSB-EP889065HU | Cusabio |
|
|
Description: Recombinant Human DNA-directed DNA/RNA polymerase mu(POLM) expressed in E.coli |
Maximo DFS-Plus Taq DNA Polymerase DNA-free |
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N140 | GeneOn | 500 units | EUR 60 |
Maximo DFS-Plus Taq DNA Polymerase DNA-free |
|||
N142 | GeneOn | 5x500 units | EUR 144 |
Maximo DFS-Plus Taq DNA Polymerase DNA-free |
|||
N144 | GeneOn | 20x500 units | EUR 440.4 |
Taq DNA polymerase (TQ21) , DNA Aptamer, FITC labeled |
|||
AD-146-F | Alpha Diagnostics | Custom | Ask for price |
pUC 18 DNA |
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MSD15 | Bio Basic | 50ug | EUR 146.65 |
pUC 19 DNA |
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MSD16 | Bio Basic | 50ug | EUR 136.21 |
pUC 57 DNA |
|||
MSD17 | Bio Basic | 50ug | EUR 136.21 |
Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (50ug Relaxed DNA + 100u Gyrase) |
|||
TG2000G-1KIT | TopoGen | 100 assays | EUR 456 |
Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (250ug Relaxed DNA + 500u Gyrase) |
|||
TG2000G-3KIT | TopoGen | 500 assays | EUR 1182 |
Human Neutrophil Elastase (DNA I) , DNA Aptamer, unlabeled |
|||
AD-155-U | Alpha Diagnostics | Custom | Ask for price |
Recombinant human DNA-directed DNA/RNA polymerase mu |
|||
P2815 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human DNA-directed DNA/RNA polymerase mu |
DNA Pure Kit |
|||
FYG601-100P | Yeastern Biotech | 100 Preps | Ask for price |
DNA Pure Kit |
|||
FYG601-300P | Yeastern Biotech | 300 Preps | Ask for price |
Taq Plus DNA |
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enz-309 | ProSpec Tany | 250U | EUR 60 |
Description: Recombinant Taq Plus DNA Polymerase |
Mouse Anti-DNA Antibody (DNA) ELISA Kit |
|||
abx257816-96tests | Abbexa | 96 tests | EUR 895.2 |
Human Neutrophil Elastase (DNA I) , DNA Aptamer, Biotinylated |
|||
AD-155-B | Alpha Diagnostics | Custom | Ask for price |
2K DNA Marker |
|||
20-abx098045 | Abbexa |
|
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5K DNA Marker |
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20-abx098048 | Abbexa |
|
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T4 DNA Ligase |
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abx098136-10kU | Abbexa | 10 kU | EUR 385.2 |
T4 DNA Ligase |
|||
abx098136-20Ku | Abbexa | 20 Ku | EUR 477.6 |
Phage λ-DNA |
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301-025 | GeneOn | 500 µg | EUR 122.4 |
Phage λ-DNA |
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301-100 | GeneOn | 5x500µg | EUR 426 |
T4 DNA ligase |
|||
402-002 | GeneOn | 400 WEISS UNITS | EUR 75.6 |
T4 DNA ligase |
|||
402-010 | GeneOn | 2000 WEISS UNITS | EUR 184.8 |
DNA Assay Kit |
|||
6023 | Chondrex | 1 kit | EUR 216.6 |
Description: DNA Assay Kit |
DNA Assay Kit |
|||
Z5030023 | Biochain | 250 assays | EUR 636 |
DNA Ligase IV |
|||
E8ET1705-77 | EnoGene | 100ul | EUR 275 |
Description: Available in various conjugation types. |
DNA Ligase I |
|||
E8ET7107-14 | EnoGene | 100ul | EUR 275 |
Description: Available in various conjugation types. |
T4 DNA Ligase |
|||
RK21501 | Abclonal | 80000U | EUR 10 |
15K DNA Marker |
|||
20-abx098049 | Abbexa |
|
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1Kb DNA Marker |
|||
20-abx098050 | Abbexa |
|
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1Kb DNA Marker |
|||
D1101-050 | GenDepot | 50㎍ | EUR 157.2 |
1Kb DNA Marker |
|||
D1101-250 | GenDepot | 5X50㎍ | EUR 360 |
DNA LADDER (1KB) |
|||
IB01351 | IBI Scientific | 50uG/500uL | EUR 61.65 |
Description: [FR] |
Taq DNA Ligase |
|||
RK20502 | Abclonal | 2000U | EUR 105 |
DiscoveryProbe? DNA Damage/DNA Repair-related Compounds Panel |
|||
L1007-5 | ApexBio | 5 mg/well | EUR 7172.4 |
Description: A wide range of well-characterized bioactive molecules that covers various targets related to DNA damage/DNA repair, including ATM/ATR, HDAC, and topoisomerase etc. Facilitate your research towards the insights of cancer, genome instability and immune diseases etc. |
Genomic DNA Kit |
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20-abx098076 | Abbexa |
|
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DNA PK Antibody |
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abx149863-100ug | Abbexa | 100 ug | EUR 526.8 |
DNA PK antibody |
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20R-1466 | Fitzgerald | 100 ug | EUR 807.6 |
Description: Rabbit polyclonal DNA PK antibody |
DNA- PK Antibody |
|||
ABF0550 | Lifescience Market | 100 ug | EUR 525.6 |
DNA PK Antibody |
|||
ABF5340 | Lifescience Market | 100 ug | EUR 525.6 |
DNA Loading Dye |
|||
G030 | ABM | 6X; 3 x 1.0 ml | EUR 94.8 |
Calf thymus DNA |
|||
HY-109517 | MedChemExpress | 100mg | EUR 2292 |
DNA LADDER (100bp) |
|||
IB01301 | IBI Scientific | 50uG/500uL | EUR 59.65 |
Description: [FR] |
DNA LADDER (100bp) |
|||
IB01302 | IBI Scientific | 50uG/500uL | EUR 56.1 |
Description: (NO LOADING DYE) [FR] |
GENOMIC DNA KIT |
|||
IB47250 | IBI Scientific | 2 X 96 PREP KIT | EUR 759.68 |
GENOMIC DNA KIT |
|||
IB47251 | IBI Scientific | 4 X 96 PREP KIT | EUR 1464.04 |
GENOMIC DNA KIT |
|||
IB47252 | IBI Scientific | 10 X 96 PREP KIT | EUR 3254.61 |
DNA PK Antibody |
|||
AF5340-100ul | Affinity Biosciences | 100ul | EUR 280 |
DNA PK Antibody |
|||
AF5340-200ul | Affinity Biosciences | 200ul | EUR 350 |
DNA PK Antibody |
|||
AF5340 | Affinity Biosciences | 100ul | EUR 280 |
Description: Human,Mouse |
DNA PK Antibody |
|||
E18-5340-1 | EnoGene | 50μg/50μl | EUR 145 |
Description: Available in various conjugation types. |
DNA PK Antibody |
|||
E18-5340-2 | EnoGene | 100μg/100μl | EUR 225 |
Description: Available in various conjugation types. |
E.coli DNA Ligase |
|||
RK20501 | Abclonal | 1000U | EUR 20.5 |
100bp DNA Marker |
|||
20-abx098052 | Abbexa |
|
|
100bp DNA ladder |
|||
9K-004-0002 | Bio Basic | 0.5ml | EUR 260.98 |
100bp DNA Marker |
|||
D1100-050 | GenDepot | 50㎍ | EUR 198 |
100bp DNA Marker |
|||
D1100-250 | GenDepot | 5X50㎍ | EUR 660 |
DNA-PKcs/PRKDC |
|||
E8M1204-6 | EnoGene | 100ul | EUR 275 |
Description: Available in various conjugation types. |
DNA pol Antibody |
|||
E18-9055-1 | EnoGene | 50ug/50ul | EUR 145 |
Description: Available in various conjugation types. |
DNA pol Antibody |
|||
E18-9055-2 | EnoGene | 100ug/100ul | EUR 225 |
Description: Available in various conjugation types. |
DNA PKcs antibody |
|||
10R-10729 | Fitzgerald | 100 ug | EUR 457.2 |
Description: Mouse monoclonal DNA PKcs antibody |
DNA PKcs antibody |
|||
20R-2017 | Fitzgerald | 50 ug | EUR 337.2 |
Description: Rabbit polyclonal DNA PKcs antibody |
DNA PKcs antibody |
|||
20R-2346 | Fitzgerald | 50 ug | EUR 337.2 |
Description: Rabbit polyclonal DNA PKcs antibody |
DNA-PK Antibody |
|||
3130-100 | Biovision | each | EUR 405.6 |
Human Genomic DNA |
|||
BIO-35025 | Bioline | 500µl @ 200ng/µl | Ask for price |
DNA PKcs antibody |
|||
70R-50261 | Fitzgerald | 100 ul | EUR 292.8 |
Description: Purified Polyclonal DNA PKcs antibody |
DNA-PK Antibody |
|||
33358-100ul | SAB | 100ul | EUR 302.4 |
DNA-PK Antibody |
|||
33358-50ul | SAB | 50ul | EUR 224.4 |
DNA PKcs Antibody |
|||
48923-100ul | SAB | 100ul | EUR 399.6 |
DNA PKcs Antibody |
|||
48923-50ul | SAB | 50ul | EUR 286.8 |
T4 DNA Polymerase |
|||
N101-01 | Vazyme | 2000 U | EUR 278.4 |
T4 DNA Polymerase |
|||
M1211-100 | Biovision | each | EUR 385.2 |
DL5000 DNA Marker |
|||
MD102-01 | Vazyme | 250 μl | EUR 128.4 |
DL5000 DNA Marker |
|||
MD102-02 | Vazyme | 500 μl | EUR 135.6 |
DNA-PK Antibody |
|||
AF0550-100ul | Affinity Biosciences | 100ul | EUR 280 |
DNA-PK Antibody |
|||
AF0550-200ul | Affinity Biosciences | 200ul | EUR 350 |
DNA polymerase mu |
|||
E8ER1907-58 | EnoGene | 100ul | EUR 275 |
Description: Available in various conjugation types. |
DNA-PK Antibody |
|||
AF6631-100ul | Affinity Biosciences | 100ul | EUR 280 |
DNA-PK Antibody |
|||
AF6631-200ul | Affinity Biosciences | 200ul | EUR 350 |
DNA-PK Antibody |
|||
AF6631 | Affinity Biosciences | 100ul | EUR 280 |
Description: Human,Mouse |
DNA-PK Antibody |
|||
AF0550 | Affinity Biosciences | 100ul | EUR 280 |
Description: Human,Mouse |
Human Genomic DNA |
|||
X11000 | EpiGentek |
|
|
DNA-PK Antibody |
|||
E11-0174C | EnoGene | 100μg/100μl | EUR 225 |
Description: Available in various conjugation types. |
DNA-PK Antibody |
|||
E11-0421B | EnoGene | 100μg | EUR 225 |
Description: Available in various conjugation types. |
DNA-PK Antibody |
|||
E11-0906B | EnoGene | 100μg | EUR 225 |
Description: Available in various conjugation types. |
DNA-PK Antibody |
|||
E11-0908B | EnoGene | 100μg | EUR 225 |
Description: Available in various conjugation types. |
DNA-PK Antibody |
|||
E11-0909B | EnoGene | 100μg | EUR 225 |
Description: Available in various conjugation types. |
DNA-PK Antibody |
|||
E033358 | EnoGene | 100μg/100μl | EUR 255 |
Description: Available in various conjugation types. |
DNA-PK Antibody |
|||
E18-0550-1 | EnoGene | 50μg/50μl | EUR 145 |
Description: Available in various conjugation types. |
DNA-PK Antibody |
|||
E18-0550-2 | EnoGene | 100μg/100μl | EUR 225 |
Description: Available in various conjugation types. |
DNA Loading Buffer |
|||
abx098143-5ml | Abbexa | 5 ml | EUR 210 |
DNA polymerase ? (Rat) |
|||
10-101 | Sceti | 20ug | EUR 465.6 |
Description: The DNA polymerase ? (Rat) is available in Europe and for worldwide shipping via Gentaur. |
DNA polymerase ? (Rat) |
|||
10-102 | Sceti | 100ug | EUR 1107.6 |
Description: The DNA polymerase ? (Rat) is available in Europe and for worldwide shipping via Gentaur. |
Taq DNA Polymerase |
|||
BA00103 | Cusabio | 500U | EUR 104.4 |
Description: High quality Taq polymerase for different PCR variations and downstream applications. |
Taq DNA Polymerase |
|||
BA00104 | Bioatlas | 1000U | EUR 147.6 |
Description: High quality Taq polymerase for different PCR variations and downstream applications. |
Taq DNA Polymerase |
|||
BA00105 | Bioatlas | 2500U | EUR 278.4 |
Description: High quality Taq polymerase for different PCR variations and downstream applications. |
Pfu DNA Polymerase |
|||
BA00503 | Bioatlas | 500U | EUR 174 |
Description: High quality Pfu polymerase for different PCR variations and downstream applications. |
Pfu DNA Polymerase |
|||
BA00504 | Bioatlas | 1000U | EUR 286.8 |
Description: High quality Pfu polymerase for different PCR variations and downstream applications. |
Pfu DNA Polymerase |
|||
BA00505 | Bioatlas | 2500U | EUR 626.4 |
Description: High quality Pfu polymerase for different PCR variations and downstream applications. |
Taq DNA polymerase |
|||
BT10101 | Bioatlas | 500U | EUR 96 |
Description: High quality Taq polymerase for different PCR variations and downstream applications. |
Taq DNA polymerase |
|||
BT10102 | Bioatlas | 1000U | EUR 130.8 |
Description: High quality Taq polymerase for different PCR variations and downstream applications. |
Taq DNA polymerase |
|||
BT10103 | Bioatlas | 2000U | EUR 200.4 |
Description: High quality Taq polymerase for different PCR variations and downstream applications. |
Taq DNA Polymerase |
|||
9001-2500 | Biovision | each | EUR 614.4 |
Taq DNA Polymerase |
|||
9001-500 | Biovision | each | EUR 229.2 |
PFU DNA Polymerase |
|||
9003-2500 | Biovision | each | EUR 614.4 |
PFU DNA Polymerase |
|||
9003-500 | Biovision | each | EUR 216 |
Laq? DNA Polymerase |
|||
9004-2500 | Biovision | each | EUR 732 |
Laq? DNA Polymerase |
|||
9004-500 | Biovision | each | EUR 261.6 |
DNA Cleared Plasma |
|||
DCP100A-1 | SBI | 100 ml | EUR 417 |
DNA Sample Diluent |
|||
D006-100 | Cygnus Technologies | 100 ml | EUR 447.6 |
Description: DNA Sample Diluent by Cygnus Technologies is available in Europe via Gentaur. |
DNA Sample Diluent |
|||
D006-1000 | Cygnus Technologies | 1000 ml | EUR 1400.4 |
Description: DNA Sample Diluent by Cygnus Technologies is available in Europe via Gentaur. |
DNA Sample Diluent |
|||
D006-500 | Cygnus Technologies | 500 ml | EUR 871.2 |
Description: DNA Sample Diluent by Cygnus Technologies is available in Europe via Gentaur. |
Taq DNA Polymerase |
|||
L7051001 | Biochain | 1000 unit | EUR 159 |
Taq DNA Polymerase |
|||
L7051200 | Biochain | 200 unit | EUR 41 |
DL15000 DNA Marker |
|||
MD103-01 | Vazyme | 250 μl | EUR 130.8 |
DL15000 DNA Marker |
|||
MD103-02 | Vazyme | 500 μl | EUR 138 |
Mycoplasma DNA Kit |
|||
K1416-250 | Biovision | each | EUR 673.2 |
Mycoplasma DNA Kit |
|||
K1416-50 | Biovision | each | EUR 379.2 |
Pfu DNA Polymerase |
|||
S116 | GeneOn | 1x250 units | EUR 91.2 |
Pfu DNA Polymerase |
|||
S117 | GeneOn | 2x250 units | EUR 112.8 |
Pfu DNA Polymerase |
|||
S118 | GeneOn | 10x250 units | EUR 363.6 |
Bst DNA Polymerase |
|||
S600 | GeneOn | 2000 U | EUR 128.4 |
Pfu DNA Polymerase |
|||
enz-265 | ProSpec Tany | 100U | EUR 145 |
Description: Recombinant Pfu DNA Polymerase |
100 bp DNA Ladder |
|||
M1158-500 | Biovision | each | EUR 333.6 |
100 bp DNA Ladder |
|||
MD104-01 | Vazyme | 250 μl | EUR 132 |
100 bp DNA Ladder |
|||
MD104-02 | Vazyme | 500 μl | EUR 139.2 |
100 bp DNA Ladder |
|||
RM19007 | Abclonal | 500μL | EUR 138 |
DNA ligase Antibody |
|||
20-abx110554 | Abbexa |
|
|
Circulating DNA Kit |
|||
abx098870-50rxns | Abbexa | 50 rxns | EUR 477.6 |
MyFi DNA Polymerase |
|||
BIO-21117 | Bioline | 250 Units | Ask for price |
MyFi DNA Polymerase |
|||
BIO-21117/S | Bioline | Sample | Ask for price |
MyFi DNA Polymerase |
|||
BIO-21118 | Bioline | 500 Units | Ask for price |
MyFi DNA Polymerase |
|||
BIO-21119 | Bioline | 2500 Units | Ask for price |
CHO DNA Concentrate |
|||
D552 | Cygnus Technologies | 1 ml | EUR 650.4 |
Description: CHO DNA Concentrate by Cygnus Technologies is available in Europe via Gentaur. |
CHO DNA Concentrate |
|||
D556 | Cygnus Technologies | 120 ul | EUR 562.8 |
Description: CHO DNA Concentrate by Cygnus Technologies is available in Europe via Gentaur. |
Circulating DNA Kit |
|||
abx298027-50rxns | Abbexa | 50 rxns | EUR 477.6 |
DNA-PKcs Antibody |
|||
R31076 | NSJ Bioreagents | 100 ug | EUR 356.15 |
Description: Protein Kinase DNA-Activated catalytic subunit, also called DNAPK, HYRC1, p350 or DNPK1, is an enzyme that in humans is encoded by the PRKDC gene. DNA-PKcs belongs to the phosphatidylinositol 3-kinase-related kinase protein family. Satoh et al.(1997) mapped the MCM4 gene to 8q11.2 by FISH. Based on the close proximity of the PRKDC and MCM4 genes, it was assumed that the PRKDC gene also maps to this location. Anderson and Lees-Miller(1992) noted that DNA-PKcs had been shown in vitro to phosphorylate several transcription factors, suggesting that it functions in cell homeostasis by modulating transcription. Daniel et al.(1999) demonstrated that the DNA-PKcs protein participates in retroviral DNA integration, which is catalyzed by the viral protein integrase. |
DNA Destaining Bags |
|||
10550021-1 | Bio-WORLD | 25 Bag (s) | EUR 85.81 |
DNA Polymerase beta |
|||
E8ET1705-12 | EnoGene | 100ul | EUR 275 |
Description: Available in various conjugation types. |
DNA-PKcs Antibody |
|||
E2200618 | EnoGene | 100ug | EUR 255 |
Description: Available in various conjugation types. |
ClearSight DNA Stain |
|||
BH40501 | Bioatlas | 1ml | EUR 123.6 |
Description: For DNA staining and vizualization. |
MyTaq DNA Polymerase |
|||
BIO-21105 | Bioline | 500 units | Ask for price |
MyTaq DNA Polymerase |
|||
BIO-21105/S | Bioline | Sample | Ask for price |
MyTaq DNA Polymerase |
|||
BIO-21106 | Bioline | 2500 units | Ask for price |
MyTaq DNA Polymerase |
|||
BIO-21107 | Bioline | 5000 units | Ask for price |
E.coli DNA Concentrate |
|||
D412 | Cygnus Technologies | 1 ml | EUR 650.4 |
Description: E.coli DNA Concentrate by Cygnus Technologies is available in Europe via Gentaur. |
DNA Storage Solution |
|||
LB3401010 | Biochain | 10 ml | EUR 34 |
DNA Concentrator Kit |
|||
P-1006 | EpiGentek |
|
|
Ready? DNA Polymerase |
|||
M1146-1000 | Biovision | each | EUR 398.4 |
Ready? DNA Polymerase |
|||
M1146-10000 | Biovision | each | EUR 1279.2 |
Ready? DNA Polymerase |
|||
M1146-5000 | Biovision | each | EUR 960 |
Phi29 DNA Polymerase |
|||
M1239-1000 | Biovision | each | EUR 373.2 |
Kodaq DNA Polymerase |
|||
G498 | ABM | 250 U (50 ul) | EUR 104.4 |
Kodaq DNA Polymerase |
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G499 | ABM | 1000 U (200 ul) | EUR 189.6 |
DNA polymerase delta |
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E8ER1907-56 | EnoGene | 100ul | EUR 275 |
Description: Available in various conjugation types. |
phi29 DNA Polymerase |
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RK21002 | Abclonal | 1250U | EUR 4 |
HotTaq DNA Polymerase |
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BA00203 | Bioatlas | 500U | EUR 174 |
Description: High quality HotTaq polymerase for different PCR variations and downstream applications. |
HotTaq DNA Polymerase |
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BA00204 | Bioatlas | 1000U | EUR 286.8 |
Description: High quality HotTaq polymerase for different PCR variations and downstream applications. |
HotTaq DNA Polymerase |
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BA00205 | Bioatlas | 2500U | EUR 626.4 |
Description: High quality HotTaq polymerase for different PCR variations and downstream applications. |
RedTaq DNA Polymerase |
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BA00303 | Bioatlas | 500U | EUR 147.6 |
Description: High quality RedTaq polymerase for different PCR variations and downstream applications. |
RedTaq DNA Polymerase |
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BA00304 | Bioatlas | 1000U | EUR 235.2 |
Description: High quality RedTaq polymerase for different PCR variations and downstream applications. |
RedTaq DNA Polymerase |
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BA00305 | Bioatlas | 2500U | EUR 495.6 |
Description: High quality RedTaq polymerase for different PCR variations and downstream applications. |
BIOTAQ DNA Polymerase |
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BIO-21040 | Bioline | 500 Units | Ask for price |
BIOTAQ DNA Polymerase |
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BIO-21060 | Bioline | 2500 Units | Ask for price |
Ranger DNA Polymerase |
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BIO-21121 | Bioline | 250 Units | Ask for price |
Ranger DNA Polymerase |
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BIO-21121/S | Bioline | Sample | Ask for price |
Ranger DNA Polymerase |
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BIO-21122 | Bioline | 500 Units | Ask for price |
HotTaq DNA polymerase |
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BT10201 | Bioatlas | 500U | EUR 144 |
Description: High quality HotTaq polymerase for different PCR variations and downstream applications. |
HotTaq DNA polymerase |
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BT10202 | Bioatlas | 1000U | EUR 228 |
Description: High quality HotTaq polymerase for different PCR variations and downstream applications. |
Human DNA Concentrate |
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D162 | Cygnus Technologies | 1 ml | EUR 607.2 |
Description: Human DNA Concentrate by Cygnus Technologies is available in Europe via Gentaur. |
AceTaq DNA Polymerase |
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P401-d1 | Vazyme | 250 U | EUR 163.2 |
AceTaq DNA Polymerase |
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P401-d2 | Vazyme | 1000 U | EUR 272.4 |
AceTaq DNA Polymerase |
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P401-d3 | Vazyme | 3000 U | EUR 536.4 |
Implementation of the UCSC Genome Browser provides additional customized layer of gene regulation accounting for individual transcript isoforms (eg, epigenetic, miRNA-binding sites and RNA-binding protein). TREND-DB that encourages APA outlines roles for various biological program, including potential disease mechanisms, and help identify potential diagnostic and therapeutic them.