Oxidized low-density lipoprotein (oxLDLs) and oxysterols play a key role in the development of endothelial dysfunction and atherosclerosis. Loss of function of vascular endothelium negative impact vasomotion, cell growth, adhesiveness and barrier function. While for some of these disorders plausible explanation can be provided from a mechanistic standpoint, for many others, the molecular players involved are not known. Caveolae, specific plasma membrane domains, has recently emerged as a target and mediator of oxLDL-induced endothelial dysfunction (ED).
Caveolae and their protein Caveolin-1 related (Cav-1) involved in oxLDLs / LDL transcytosis, especially through the scavenger receptor class B type 1 (SR-B1). Instead, oxLDLs LDL receptor endocytosis mediated by lectin-like oxidized 1 (LOX-1), whose activities depend on intact caveolae system. In addition, LOX-1 regulates expression of Cav-1 and vice versa.
On the other hand, oxLDLs may affect the plasma membrane cholesterol content / distribution thus affecting the architecture of caveolae, Cav-1 localization and related signals. Overall, this body of evidence shows that caveolae have both active and passive role in oxLDL-induced EC dysfunction. First as a mediator of lipid uptake and transfer in the subendothelial space, and then, as the target of a change in the composition / plasma membrane lipid dynamics resulting from increased levels of circulating oxLDLs.
Getting a better understanding of how oxLDLs interacts with endothelial cells (EC) and caveolae-mediated signaling pathways modulate, leading to ED, it is important to find new targets of intervention to address atherosclerosis and related clinical entities.
Thiol-based switching mechanism of stress-sensing companion
Thiol-based redox switches evolved as post-translational mechanisms that allow for efficient regulation of individual proteins to quickly respond to sudden environmental changes. While some of the functions of proteins need to be turned off to conserve resources and avoid potentially error-prone process, the protective function becomes important and need to be activated. In this review, we focus on the mechanism of thiol-based activation of the stress-sensing chaperones.
After the exposure to stress, the companion converted into a high-affinity binding platform for ongoing proteins and cells to protect against the accumulation of protein aggregates that are potentially toxic. their chaperone activity independent of ATP, a feature that is very important in conditions of oxidative stress, in which cellular ATP levels drop and canonical ATP-dependent chaperone no longer operate.
Likewise, reductive inactivation and release substrates require recovery of ATP levels, which ensures clients with foldases protein folding ATP-dependent. We will provide an overview on the different strategies that cells evolved to rapidly increase an ATP-independent chaperone on oxidative stress and provide mechanistic insight into how stress conditions used to convert the cellular protein overflow into the holding ATP-independent chaperones.
Both lysosomal integral membrane proteins form a complex MFSD1 and GLMP tight that confer protection from both interaction partners against lysosomal proteolysis. We are here enhanced molecular interactions of the two proteins and found that GLMP luminal domain, but not the transmembrane domain or short cytosolic tail, the inherent protection and mediate interactions with MFSD1.Our data support the finding that the interaction is important for the stabilization of the complex.
These results are supplemented by observations that N-glycosylation of GLMP in general, but not the type N-glycans (high-mannose-type or complex-type) or individual N-glycan chains, it is very important for protection. We observed that the interaction of the two proteins has already begun in the endoplasmic reticulum, and quantitative dependent on one another.
Both proteins can affect otherwise their intracellular trafficking to lysosomes in addition to protection from proteolysis. Finally, we provide evidence that can form homodimers MFSD1 both in vitro and in vivo. Our data repair complex interaction between intimate partner of the lysosomal transporter and accessory subunit.
TREND-DB-atlas transcriptome-wide dynamic landscape of alternative polyadenylation
alternative polyadenylation (APA) extend deep transcriptome complexity. Disruption of the APA can interfere with biological processes, ultimately resulting in disruption destroy. The main challenge in identifying the mechanisms and consequences of APA (and its disturbances) lies in the complexity of the RNA 3 ‘end processing, which involves poorly conserved RNA motif and multi-component complex consisting of more than 50 proteins.
It is more complicated that the RNA 3 ‘end maturation closely associated with transcription, RNA processing and even epigenetic (histone / DNA / RNA) modification. Here, we present TREND-DB , resource cataloging dynamic landscape APA after depletion> 170 proteins involved in various aspects of transcription, gene regulation co- and post-transcriptional, and epigenetic modifications further processing. TREND-DB visualization transcriptome dynamics 3 ‘diversification end (TREND) in a very interactive; APA provides global network maps and allows interrogating genes influenced by APA-specific regulator and vice versa. It also allows the analysis of functional enrichment of specific conditions WHAT affected genes, which show wide biological and clinical relevance in all conditions of RNAi.
 DiscoveryProbe? DNA Damage/DNA Repair Library |
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| L1033-5 | ApexBio | 5 mg/well | EUR 9005 |
 pUC18 DNA |
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| G40-300 | GeneOn | 50µg | EUR 56 |
|
pUC18 DNA |
|||
| G40-305 | GeneOn | 5x50µg | EUR 147 |
 DNA Antibody |
|||
| abx023805-02mg | Abbexa | 0.2 mg | EUR 648 |
|
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 DNA Polymerase |
|||
| ABF5235 | Lifescience Market | 100 ug | EUR 438 |
 DNA pol |
|||
| ABF9055 | Lifescience Market | 100 ug | EUR 438 |
|
DNA Polymerase |
|||
| ABD3082 | Lifescience Market | 100 ug | EUR 438 |
 DNA antibody |
|||
| 10C-CR6034M1 | Fitzgerald | 100 ug | EUR 241 |
|
Description: Mouse monoclonal DNA antibody |
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|
DNA antibody |
|||
| 10-D20A | Fitzgerald | 500 ug | EUR 493 |
|
Description: Mouse monoclonal DNA antibody |
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DNA antibody |
|||
| 10R-D114b | Fitzgerald | 100 ug | EUR 560 |
|
Description: Mouse monoclonal DNA antibody |
|||
 T7 DNA |
|||
| 310-005 | GeneOn | 200µg | EUR 82 |
|
T7 DNA |
|||
| 310-025 | GeneOn | 5x200 µg | EUR 225 |
 DNA-Fect |
|||
| DF37100-1 | Neuromics | 1 ml | EUR 349 |
 DNA-Fect293 |
|||
| DF37293-1 | Neuromics | 1 ml | EUR 291 |
 pBR322 DNA |
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| MSD14 | Bio Basic | 50ug | EUR 152.66 |
|
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 DNA-fectamine |
|||
| DNAF001 | Bio Basic | 1ml | EUR 278.81 |
|
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 , DNA Aptamer, Biotinylated) Taq DNA polymerase (TQ21) , DNA Aptamer, Biotinylated |
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| AD-146-B | Alpha Diagnostics | Custom | Ask for price |
 , DNA Aptamer, unlabeled) Taq DNA polymerase (TQ21) , DNA Aptamer, unlabeled |
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| AD-146-U | Alpha Diagnostics | Custom | Ask for price |
 ELISA Kit) Mouse Anti-DNA Antibody (DNA) ELISA Kit |
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| abx257816-96tests | Abbexa | 96 tests | EUR 746 |
|
|||
 Antibody) DNA Ligase I (DNA Ligase I) Antibody |
|||
| abx232431-100ug | Abbexa | 100 ug | EUR 481 |
|
|||
 DFS-"HOT" Taq DNA Polymerase (DNA-free sensitive, E-coli. DNA Free) |
|||
| N150 | GeneOn | 500 units | EUR 102 |
|
DFS-"HOT" Taq DNA Polymerase (DNA-free sensitive, E-coli. DNA Free) |
|||
| N152 | GeneOn | 5x500 units | EUR 394 |
|
DFS-"HOT" Taq DNA Polymerase (DNA-free sensitive, E-coli. DNA Free) |
|||
| N154 | GeneOn | 20x500 units | EUR 1525 |
 , DNA Aptamer, FITC labeled) Taq DNA polymerase (TQ21) , DNA Aptamer, FITC labeled |
|||
| AD-146-F | Alpha Diagnostics | Custom | Ask for price |
 , DNA Aptamer, Biotinylated) Human Neutrophil Elastase (DNA I) , DNA Aptamer, Biotinylated |
|||
| AD-155-B | Alpha Diagnostics | Custom | Ask for price |
 , DNA Aptamer, unlabeled) Human Neutrophil Elastase (DNA I) , DNA Aptamer, unlabeled |
|||
| AD-155-U | Alpha Diagnostics | Custom | Ask for price |
) Human DNA-directed DNA/RNA polymerase mu (POLM) |
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| 1-CSB-YP889065HU | Cusabio |
|
|
|
|||
|
Description: Recombinant Human DNA-directed DNA/RNA polymerase mu(POLM) expressed in Yeast |
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Human DNA-directed DNA/RNA polymerase mu (POLM) |
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| 1-CSB-EP889065HU | Cusabio |
|
|
|
|||
|
Description: Recombinant Human DNA-directed DNA/RNA polymerase mu(POLM) expressed in E.coli |
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Human DNA-directed DNA/RNA polymerase mu (POLM) |
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| 1-CSB-BP889065HU | Cusabio |
|
|
|
|||
|
Description: Recombinant Human DNA-directed DNA/RNA polymerase mu(POLM) expressed in Baculovirus |
|||
 Maximo DFS-Plus Taq DNA Polymerase DNA-free |
|||
| N140 | GeneOn | 500 units | EUR 50 |
|
Maximo DFS-Plus Taq DNA Polymerase DNA-free |
|||
| N142 | GeneOn | 5x500 units | EUR 120 |
|
Maximo DFS-Plus Taq DNA Polymerase DNA-free |
|||
| N144 | GeneOn | 20x500 units | EUR 367 |
 DiscoveryProbe? DNA Damage/DNA Repair-related Compounds Panel |
|||
| L1007-5 | ApexBio | 5 mg/well | EUR 5977 |
|
Description: A wide range of well-characterized bioactive molecules that covers various targets related to DNA damage/DNA repair, including ATM/ATR, HDAC, and topoisomerase etc. Facilitate your research towards the insights of cancer, genome instability and immune diseases etc. |
|||
 Recombinant human DNA-directed DNA/RNA polymerase mu |
|||
| P2815 | FN Test | 100ug | Ask for price |
|
|||
|
Description: Recombinant protein for human DNA-directed DNA/RNA polymerase mu |
|||
 DNA PK Antibody |
|||
| AF5340 | Affbiotech | 200ul | EUR 304 |
|
Description: DNA PK Antibody detects endogenous levels of total DNA PK. |
|||
 ClearSight DNA Stain |
|||
| BH40501 | Bioatlas | 1ml | EUR 103 |
|
Description: For DNA staining and vizualization. |
|||
 BIOTAQ DNA Polymerase |
|||
| BIO-21040 | Bioline | 500 Units | Ask for price |
 IMMOLASE DNA Polymerase |
|||
| BIO-21046 | Bioline | 250 Units | Ask for price |
|
IMMOLASE DNA Polymerase |
|||
| BIO-21047 | Bioline | 500 Units | Ask for price |
|
IMMOLASE DNA Polymerase |
|||
| BIO-21048 | Bioline | 5000 Units | Ask for price |
 ACCUZYME DNA Polymerase |
|||
| BIO-21051 | Bioline | 250 Units | Ask for price |
|
ACCUZYME DNA Polymerase |
|||
| BIO-21052 | Bioline | 500 Units | Ask for price |
|
BIOTAQ DNA Polymerase |
|||
| BIO-21060 | Bioline | 2500 Units | Ask for price |
 MangoTaq DNA Polymerase |
|||
| BIO-21078 | Bioline | 5000 Units | Ask for price |
|
MangoTaq DNA Polymerase |
|||
| BIO-21082 | Bioline | 2000 Units | Ask for price |
|
MangoTaq DNA Polymerase |
|||
| BIO-21083 | Bioline | 1000 Units | Ask for price |
 VELOCITY DNA Polymerase |
|||
| BIO-21098 | Bioline | 250 Units | Ask for price |
|
VELOCITY DNA Polymerase |
|||
| BIO-21099 | Bioline | 500 Units | Ask for price |
 MyTaq DNA Polymerase |
|||
| BIO-21105 | Bioline | 500 units | Ask for price |
|
MyTaq DNA Polymerase |
|||
| BIO-21105/S | Bioline | Sample | Ask for price |
|
MyTaq DNA Polymerase |
|||
| BIO-21106 | Bioline | 2500 units | Ask for price |
|
MyTaq DNA Polymerase |
|||
| BIO-21107 | Bioline | 5000 units | Ask for price |
 MyFi DNA Polymerase |
|||
| BIO-21117 | Bioline | 250 Units | Ask for price |
|
MyFi DNA Polymerase |
|||
| BIO-21117/S | Bioline | Sample | Ask for price |
|
MyFi DNA Polymerase |
|||
| BIO-21118 | Bioline | 500 Units | Ask for price |
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MyFi DNA Polymerase |
|||
| BIO-21119 | Bioline | 2500 Units | Ask for price |
 Ranger DNA Polymerase |
|||
| BIO-21121 | Bioline | 250 Units | Ask for price |
|
Ranger DNA Polymerase |
|||
| BIO-21121/S | Bioline | Sample | Ask for price |
|
Ranger DNA Polymerase |
|||
| BIO-21122 | Bioline | 500 Units | Ask for price |
 Human Genomic DNA |
|||
| BIO-35025 | Bioline | 500µl @ 200ng/µl | Ask for price |
 Taq DNA Polymerase |
|||
| BA00103 | Cusabio | 500U | EUR 87 |
|
Description: High quality Taq polymerase for different PCR variations and downstream applications. |
|||
|
Taq DNA Polymerase |
|||
| BA00104 | Bioatlas | 1000U | EUR 123 |
|
Description: High quality Taq polymerase for different PCR variations and downstream applications. |
|||
|
Taq DNA Polymerase |
|||
| BA00105 | Bioatlas | 2500U | EUR 232 |
|
Description: High quality Taq polymerase for different PCR variations and downstream applications. |
|||
 HotTaq DNA Polymerase |
|||
| BA00203 | Bioatlas | 500U | EUR 145 |
|
Description: High quality HotTaq polymerase for different PCR variations and downstream applications. |
|||
|
HotTaq DNA Polymerase |
|||
| BA00204 | Bioatlas | 1000U | EUR 239 |
|
Description: High quality HotTaq polymerase for different PCR variations and downstream applications. |
|||
|
HotTaq DNA Polymerase |
|||
| BA00205 | Bioatlas | 2500U | EUR 522 |
|
Description: High quality HotTaq polymerase for different PCR variations and downstream applications. |
|||
 RedTaq DNA Polymerase |
|||
| BA00303 | Bioatlas | 500U | EUR 123 |
|
Description: High quality RedTaq polymerase for different PCR variations and downstream applications. |
|||
|
RedTaq DNA Polymerase |
|||
| BA00304 | Bioatlas | 1000U | EUR 196 |
|
Description: High quality RedTaq polymerase for different PCR variations and downstream applications. |
|||
|
RedTaq DNA Polymerase |
|||
| BA00305 | Bioatlas | 2500U | EUR 413 |
|
Description: High quality RedTaq polymerase for different PCR variations and downstream applications. |
|||
 Pfu DNA Polymerase |
|||
| BA00503 | Bioatlas | 500U | EUR 145 |
|
Description: High quality Pfu polymerase for different PCR variations and downstream applications. |
|||
|
Pfu DNA Polymerase |
|||
| BA00504 | Bioatlas | 1000U | EUR 239 |
|
Description: High quality Pfu polymerase for different PCR variations and downstream applications. |
|||
|
Pfu DNA Polymerase |
|||
| BA00505 | Bioatlas | 2500U | EUR 522 |
|
Description: High quality Pfu polymerase for different PCR variations and downstream applications. |
|||
 Taq DNA polymerase |
|||
| BT10101 | Bioatlas | 500U | EUR 80 |
|
Description: High quality Taq polymerase for different PCR variations and downstream applications. |
|||
|
Taq DNA polymerase |
|||
| BT10102 | Bioatlas | 1000U | EUR 109 |
|
Description: High quality Taq polymerase for different PCR variations and downstream applications. |
|||
|
Taq DNA polymerase |
|||
| BT10103 | Bioatlas | 2000U | EUR 167 |
|
Description: High quality Taq polymerase for different PCR variations and downstream applications. |
|||
 HotTaq DNA polymerase |
|||
| BT10201 | Bioatlas | 500U | EUR 120 |
|
Description: High quality HotTaq polymerase for different PCR variations and downstream applications. |
|||
|
HotTaq DNA polymerase |
|||
| BT10202 | Bioatlas | 1000U | EUR 190 |
|
Description: High quality HotTaq polymerase for different PCR variations and downstream applications. |
|||
 DNA-PK Antibody |
|||
| AF0550 | Affbiotech | 200ul | EUR 304 |
|
Description: DNA-PK Antibody detects endogenous levels of DNA-PK. |
|||
 Calf thymus DNA |
|||
| HY-109517 | MedChemExpress | 100mg | EUR 1910 |
 DNA Pure Kit |
|||
| FYG601-100P | Yeastern Biotech | 100 Preps | Ask for price |
|
DNA Pure Kit |
|||
| FYG601-300P | Yeastern Biotech | 300 Preps | Ask for price |
 DNA Loading Dye |
|||
| G030 | ABM | 6X; 3 x 1.0 ml | EUR 79 |
 Kodaq DNA Polymerase |
|||
| G498 | ABM | 250 U (50 ul) | EUR 87 |
|
Kodaq DNA Polymerase |
|||
| G499 | ABM | 1000 U (200 ul) | EUR 158 |
 DNA ligase Antibody |
|||
| 20-abx110554 | Abbexa |
|
|
|
|||
 Sapphire Baculovirus DNA |
|||
| ABP-BVD-10001 | Allele Biotech | 15 µg (10 rxns) | Ask for price |
|
|||
|
DNA PK Antibody |
|||
| abx149863-100ug | Abbexa | 100 ug | EUR 439 |
|
|||
 2K DNA Marker |
|||
| 20-abx098045 | Abbexa |
|
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|
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 5K DNA Marker |
|||
| 20-abx098048 | Abbexa |
|
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|
|||
 15K DNA Marker |
|||
| 20-abx098049 | Abbexa |
|
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|
|||
 1Kb DNA Marker |
|||
| 20-abx098050 | Abbexa |
|
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|
|||
 100bp DNA Marker |
|||
| 20-abx098052 | Abbexa |
|
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|
|||
 Genomic DNA Kit |
|||
| 20-abx098076 | Abbexa |
|
|
|
|||
 T4 DNA Ligase |
|||
| abx098136-10kU | Abbexa | 10 kU | EUR 321 |
|
|||
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T4 DNA Ligase |
|||
| abx098136-20Ku | Abbexa | 20 Ku | EUR 398 |
|
|||
 DNA Loading Buffer |
|||
| abx098143-5ml | Abbexa | 5 ml | EUR 175 |
|
|||
 Circulating DNA Kit |
|||
| abx098870-50rxns | Abbexa | 50 rxns | EUR 398 |
|
|||
 Intercalated DNA Antibody |
|||
| abx020668-02mg | Abbexa | 0.2 mg | EUR 523 |
|
|||
|
DNA PK Antibody |
|||
| ABF5340 | Lifescience Market | 100 ug | EUR 438 |
 DNA- PK Antibody |
|||
| ABF0550 | Lifescience Market | 100 ug | EUR 438 |
|
Circulating DNA Kit |
|||
| abx298027-50rxns | Abbexa | 50 rxns | EUR 398 |
|
|||
 DNA PKcs antibody |
|||
| 70R-50261 | Fitzgerald | 100 ul | EUR 244 |
|
Description: Purified Polyclonal DNA PKcs antibody |
|||
|
Taq DNA Polymerase |
|||
| 9001-2500 | Biovision | EUR 512 | |
|
Taq DNA Polymerase |
|||
| 9001-500 | Biovision | EUR 191 | |
 PFU DNA Polymerase |
|||
| 9003-2500 | Biovision | EUR 512 | |
|
PFU DNA Polymerase |
|||
| 9003-500 | Biovision | EUR 180 | |
 Laq? DNA Polymerase |
|||
| 9004-2500 | Biovision | EUR 610 | |
|
Laq? DNA Polymerase |
|||
| 9004-500 | Biovision | EUR 218 | |
 T4 DNA ligase |
|||
| 402-002 | GeneOn | 400 WEISS UNITS | EUR 63 |
|
T4 DNA ligase |
|||
| 402-010 | GeneOn | 2000 WEISS UNITS | EUR 154 |
 DNA PKcs Antibody |
|||
| 48923-100ul | SAB | 100ul | EUR 333 |
|
DNA PKcs Antibody |
|||
| 48923-50ul | SAB | 50ul | EUR 239 |
|
DNA PKcs antibody |
|||
| 10R-10729 | Fitzgerald | 100 ug | EUR 381 |
|
Description: Mouse monoclonal DNA PKcs antibody |
|||
) DNA polymerase ? (Rat) |
|||
| 10-101 | Sceti | 20ug | EUR 388 |
|
Description: The DNA polymerase ? (Rat) is available in Europe and for worldwide shipping via Gentaur. |
|||
|
DNA polymerase ? (Rat) |
|||
| 10-102 | Sceti | 100ug | EUR 923 |
|
Description: The DNA polymerase ? (Rat) is available in Europe and for worldwide shipping via Gentaur. |
|||
|
DNA-PK Antibody |
|||
| 3130-100 | Biovision | EUR 338 | |
 Phage λ-DNA |
|||
| 301-025 | GeneOn | 500 µg | EUR 102 |
|
Phage λ-DNA |
|||
| 301-100 | GeneOn | 5x500µg | EUR 355 |
|
DNA-PK Antibody |
|||
| 33358-100ul | SAB | 100ul | EUR 252 |
|
DNA-PK Antibody |
|||
| 33358-50ul | SAB | 50ul | EUR 187 |
 DNA PK antibody |
|||
| 20R-1466 | Fitzgerald | 100 ug | EUR 673 |
|
Description: Rabbit polyclonal DNA PK antibody |
|||
 Z-DNA antibody |
|||
| 20-ZS20 | Fitzgerald | 250 ug | EUR 421 |
|
Description: Sheep polyclonal Z-DNA antibody |
|||
|
DNA PKcs antibody |
|||
| 20R-2017 | Fitzgerald | 50 ug | EUR 281 |
|
Description: Rabbit polyclonal DNA PKcs antibody |
|||
|
DNA PKcs antibody |
|||
| 20R-2346 | Fitzgerald | 50 ug | EUR 281 |
|
Description: Rabbit polyclonal DNA PKcs antibody |
|||
 DNA Assay Kit |
|||
| 6023 | Chondrex | 1 kit | EUR 180.5 |
|
Description: DNA Assay Kit |
|||
 Uracil DNA Glycosylase |
|||
| 7-03778 | CHI Scientific | 2,000U | Ask for price |
|
Uracil DNA Glycosylase |
|||
| 7-03779 | CHI Scientific | 10,000U | Ask for price |
|
Uracil DNA Glycosylase |
|||
| 7-03780 | CHI Scientific | 20,000U | Ask for price |
 Mycoplasma DNA Kit |
|||
| K1416-250 | Biovision | EUR 561 | |
|
Mycoplasma DNA Kit |
|||
| K1416-50 | Biovision | EUR 316 | |
 DNA Sample Diluent |
|||
| D006-100 | Cygnus Technologies | 100 ml | EUR 373 |
|
|||
|
Description: DNA Sample Diluent by Cygnus Technologies is available in Europe via Gentaur. |
|||
|
DNA Sample Diluent |
|||
| D006-1000 | Cygnus Technologies | 1000 ml | EUR 1167 |
|
|||
|
Description: DNA Sample Diluent by Cygnus Technologies is available in Europe via Gentaur. |
|||
|
DNA Sample Diluent |
|||
| D006-500 | Cygnus Technologies | 500 ml | EUR 726 |
|
|||
|
Description: DNA Sample Diluent by Cygnus Technologies is available in Europe via Gentaur. |
|||
 DNA Precipitation Buffer |
|||
| D106 | Cygnus Technologies | 55 ml | EUR 175 |
|
|||
|
Description: DNA Precipitation Buffer by Cygnus Technologies is available in Europe via Gentaur. |
|||
|
100bp DNA Marker |
|||
| D1100-050 | GenDepot | 50㎍ | EUR 165 |
|
100bp DNA Marker |
|||
| D1100-250 | GenDepot | 5X50㎍ | EUR 550 |
|
1Kb DNA Marker |
|||
| D1101-050 | GenDepot | 50㎍ | EUR 131 |
|
1Kb DNA Marker |
|||
| D1101-250 | GenDepot | 5X50㎍ | EUR 300 |
 Human DNA Concentrate |
|||
| D162 | Cygnus Technologies | 1 ml | EUR 506 |
|
|||
|
Description: Human DNA Concentrate by Cygnus Technologies is available in Europe via Gentaur. |
|||
 E.coli DNA Concentrate |
|||
| D412 | Cygnus Technologies | 1 ml | EUR 542 |
|
|||
|
Description: E.coli DNA Concentrate by Cygnus Technologies is available in Europe via Gentaur. |
|||
 CHO DNA Concentrate |
|||
| D552 | Cygnus Technologies | 1 ml | EUR 542 |
|
|||
|
Description: CHO DNA Concentrate by Cygnus Technologies is available in Europe via Gentaur. |
|||
|
CHO DNA Concentrate |
|||
| D556 | Cygnus Technologies | 120 ul | EUR 469 |
|
|||
|
Description: CHO DNA Concentrate by Cygnus Technologies is available in Europe via Gentaur. |
|||
 T4 DNA Polymerase |
|||
| N101-01 | Vazyme | 2000 U | EUR 232 |
 DL5000 DNA Marker |
|||
| MD102-01 | Vazyme | 250 μl | EUR 107 |
|
DL5000 DNA Marker |
|||
| MD102-02 | Vazyme | 500 μl | EUR 113 |
 DL15000 DNA Marker |
|||
| MD103-01 | Vazyme | 250 μl | EUR 109 |
|
DL15000 DNA Marker |
|||
| MD103-02 | Vazyme | 500 μl | EUR 115 |
|
T4 DNA Polymerase |
|||
| M1211-100 | Biovision | EUR 321 | |
|
Uracil DNA Glycosylase |
|||
| M1234-1000 | Biovision | EUR 213 | |
 Phi29 DNA Polymerase |
|||
| M1239-1000 | Biovision | EUR 311 | |
 Ready? DNA Polymerase |
|||
| M1146-1000 | Biovision | EUR 332 | |
|
Ready? DNA Polymerase |
|||
| M1146-10000 | Biovision | EUR 1066 | |
|
Ready? DNA Polymerase |
|||
| M1146-5000 | Biovision | EUR 800 | |
 Breeze? DNA Polymerase |
|||
| M1148-1000 | Biovision | EUR 1039 | |
|
Breeze? DNA Polymerase |
|||
| M1148-250 | Biovision | EUR 387 | |
 Distant? DNA Polymerase |
|||
| M1150-1000 | Biovision | EUR 686 | |
|
Distant? DNA Polymerase |
|||
| M1150-250 | Biovision | EUR 278 | |
 Advance? DNA Polymerase |
|||
| M1151-1000 | Biovision | EUR 746 | |
|
Advance? DNA Polymerase |
|||
| M1151-250 | Biovision | EUR 311 | |
 Outstretched? DNA Polymerase |
|||
| M1152-1000 | Biovision | EUR 800 | |
|
Outstretched? DNA Polymerase |
|||
| M1152-250 | Biovision | EUR 332 | |
|
Taq DNA Polymerase |
|||
| L7051001 | Biochain | 1000 unit | EUR 195 |
|
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol. |
|||
|
Taq DNA Polymerase |
|||
| L7051200 | Biochain | 200 unit | EUR 87 |
|
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol. |
|||
 DNA Storage Solution |
|||
| LB3401010 | Biochain | 10 ml | EUR 79 |
|
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol. |
|||
 DNA Concentrator Kit |
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| P-1006 | EpiGentek | 100 Samples | EUR 253 |
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Description: Ask the seller for details |
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 AceTaq DNA Polymerase |
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| P401-d1 | Vazyme | 250 U | EUR 136 |
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AceTaq DNA Polymerase |
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| P401-d2 | Vazyme | 1000 U | EUR 227 |
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AceTaq DNA Polymerase |
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| P401-d3 | Vazyme | 3000 U | EUR 447 |
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Pfu DNA Polymerase |
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| S116 | GeneOn | 1x250 units | EUR 76 |
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Pfu DNA Polymerase |
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| S117 | GeneOn | 2x250 units | EUR 94 |
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Pfu DNA Polymerase |
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| S118 | GeneOn | 10x250 units | EUR 303 |
 Bst DNA Polymerase |
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| S600 | GeneOn | 2000 U | EUR 107 |
 Uracil DNA Glycosilase |
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| RP-1470 | Alpha Diagnostics | 2000 IU | EUR 286 |
) Kinetoplast DNA (catenated) |
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| TG2013-1 | TopoGen | 25 ug | EUR 268 |
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Kinetoplast DNA (catenated) |
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| TG2013-2 | TopoGen | 50 ug | EUR 380 |
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Kinetoplast DNA (catenated) |
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| TG2013-3 | TopoGen | 250 ug | EUR 1052 |
 anti-DNA PKcs |
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| YF-PA24465 | Abfrontier | 50 ul | EUR 334 |
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Description: Mouse polyclonal to DNA PKcs |
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DNA Assay Kit |
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| Z5030023 | Biochain | 250 assays | EUR 647 |
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Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol. |
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Human Genomic DNA |
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| X11000 | EpiGentek | 0.2 ml | Ask for price |
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Description: reagents widely cited |
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 pUC 18 DNA |
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| MSD15 | Bio Basic | 50ug | EUR 122.21 |
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 pUC 19 DNA |
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| MSD16 | Bio Basic | 50ug | EUR 113.51 |
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 pUC 57 DNA |
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| MSD17 | Bio Basic | 50ug | EUR 113.51 |
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 Green-DNA Dye |
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| SB2040 | Bio Basic | 100UL, 100UL | EUR 67.4 |
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 EZ-DNA Reagents |
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| SK8201 | Bio Basic | 100preps | EUR 93.5 |
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 100bp DNA ladder |
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| 9K-004-0002 | Bio Basic | 0.5ml | EUR 217.48 |
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EZ-DNA Reagents |
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| BS8202 | Bio Basic | 100preps | EUR 88.06 |
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 , DNA Aptamer, FITC labeled) Human Neutrophil Elastase (DNA I) , DNA Aptamer, FITC labeled |
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| AD-155-F | Alpha Diagnostics | Custom | Ask for price |
 n-DNA-Ab/ Rat n- DNA- Ab ELISA Kit |
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| ELA-E1126r | Lifescience Market | 96 Tests | EUR 886 |
 Antibody) DNA-Dependent Protein Kinase Catalytic Subunit (DNA-PKcs) Antibody |
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| 20-abx008825 | Abbexa |
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 Antibody) DNA-Dependent Protein Kinase Catalytic Subunit (DNA-PK) Antibody |
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| 20-abx013061 | Abbexa |
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 Antibody ELISA Kit) Human Single Stranded DNA (SS-DNA) Antibody ELISA Kit |
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| abx364935-96tests | Abbexa | 96 tests | EUR 511 |
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 Antibody ELISA Kit) Human Double Stranded DNA (DS-DNA) Antibody ELISA Kit |
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| abx364947-96tests | Abbexa | 96 tests | EUR 511 |
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DNA-Dependent Protein Kinase Catalytic Subunit (DNA-PKcs) Antibody |
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| abx232474-100ug | Abbexa | 100 ug | EUR 509 |
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 ELISA test) ds-DNA (Double-stranded DNA Antibody IgG) ELISA test |
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| 50 | Biobase | 96T/Box | Ask for price |
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Description: ELISA based test for quantitative detection of ds-DNA (Double-stranded DNA Antibody IgG) |
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 ELISA test) ss-DNA (Single-stranded DNA Antibody IgG) ELISA test |
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| 51 | Biobase | 96T/Box | Ask for price |
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Description: ELISA based test for quantitative detection of ss-DNA (Single-stranded DNA Antibody IgG) |
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) Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (50ug Relaxed DNA + 100u Gyrase) |
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| TG2000G-1KIT | TopoGen | 100 assays | EUR 380 |
) Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (250ug Relaxed DNA + 500u Gyrase) |
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| TG2000G-3KIT | TopoGen | 500 assays | EUR 985 |
) Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (500ug Relaxed DNA + 1000u Gyrase) |
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| TG2000G-5KIT | TopoGen | 1000 assays | EUR 1612 |
) Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (1mg Relaxed DNA + 2000u Gyrase) |
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| TG2000G-7KIT | TopoGen | 2000 assays | EUR 2844 |
 ELISA Kit) Human DBP/DNA Binding Protein(DNA Binding Protein) ELISA Kit |
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| EH2936 | FN Test | 96T | EUR 524.1 |
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Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
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Implementation of the UCSC Genome Browser provides additional customized layer of gene regulation accounting for individual transcript isoforms (eg, epigenetic, miRNA-binding sites and RNA-binding protein). TREND-DB that encourages APA outlines roles for various biological program, including potential disease mechanisms, and help identify potential diagnostic and therapeutic them.