Devices

Highly-flexible label-free workstations for any kind of biomolecular interaction studies. Find the suitable device for your application.

bscreen

Label-free screening of over 10,000´s of samples with kinetics on one workstation within a week

/ Primary discovery screening
/ Higher throughput for secondary screening
/ Screen for primary target along with cross reactivity
/ enriched data sets enabled by kinetics

Screen more, faster with flexible assay design and receive richer data sets enabled by kinetics.

bscreen combines microarray technology with kinetics offering richer data sets that improve target identification and provide better lead candidates for characterization, acceleration the pipeline for new drug discoveries.

  • Screen more – Screen larger data sets without the limitations of working in microplates
  • Reduce Costs – Reduce the costs of screening by using less of your valuable sample
  • Improve Workflows – Develop new workflows utilizing the accelerator lab and in-house application support
  • Save Time – Speed up the process screening 10,000+ samples in 5 days total workflow from start to data
  • Enrich Data – Enrich data sets by providing insights through kinetic information
  • Better Targets – Provide better targets for characterization by catching low affinity binders and less false positives

 

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Technology
The bscreen combines the high-throughput of classic µ-array with the high-content of kinetic measurements. Up to 22,500 independent biomolecular interactions can be analysed simultaneously to gain information about binding affinities as well as association and dissociation rates (ka and kd).

Device
The bscreen is a µ-array workstation that allows you to observe the complete binding process on each spot of your µ-array in parallel. It automates flow through incubation, dissociation, data acquisition and regeneration. Integrated powerful fluidics allow for robust and reliable measurements.

Software
Measurement, sample handling and data acquisition is automatized within an easy to use software. In addition, the complementary data evaluation package offers a powerful tool for kinetic data analysis.

Consumables
The bscreen utilizes low-cost glass type sensor chips in the standard microscopic slide format. Format and surface technology are compatible usual printing equipment and methods. The Biametrics sensor chips come equipped with various coupling chemistries.

Samples
Interaction studies can be performed with almost any type of biomolecule, ranging from proteins, peptides, DNA/RNA up to whole cells, viruses or (nano) particles. The system is compatible with standard buffers and media and even crude samples like serum or cell lysates.

bportable

A point-of-need tool for label-free biomolecular interaction analysis

/ Cost effective
/ Fast kinetic analysis
/ Easy to use plug-and-play
/ Internal calibration

Coming soon