In part one of his article Prof. Günter Roth demonstrated how “blind believe” in established methods for kinetic analysis might be misplaced trust. In this second part he explains how label-free imaging technology literally allows us a fresh look on binding kinetics.
Meet our CEO Günther at the upcoming International MicroNanoConference which will be held on December 12 and 13 in Amsterdam. Günther will give a talk on the “Application of high-throughput label-free microarrays for Biomolecular Interaction Studies”. Take the chance to discuss the latest advances in lable-free microarrays with him.
Label-free analysis has made its way in the life sciences and has become a valued tool e.g. in pharmaceutical research. This is mainly due to its outstanding depth of information in combination with its reliable data quality. Yet, many other areas of application might benefit from certain advantages of label-free methods that remained largely unexploited so far. … read more
We are happy to announce a new joint research project in the field of aptamer development. Together with our partners from the University of Freiburg (Freiburg, Germany), the Karamanoglu Mehmetbey University (Karaman, Turkey) and Nehir Biyoteknoloji (Ankara, Turkey), we will develop a novel approach for selective aptamer production. … read more
The 16th Annual World Congress of the Human Proteome Organisation, the HUPO 2017, was held in the Convention Centre in the heart of Dublin, Ireland, from 17th to 21th of September. About 950 participants from academia and industry were attracted by the Congress to discuss new proteomic approaches in the field of health, disease and ageing. … read more
We are happy to announce a new joint research project in the field of nanoparticle production. Together with our partners Goldfuß engineering GmbH (Balingen), BioTeSys GmbH (Esslingen am Neckar) and Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (Munich), we will develop a novel and flexible robotics-based approach for the production of diagnostic and/or therapeutic nanoparticles. … read more
Meet us at the upcoming HUPO held in Dublin, Ireland, from September 17 to 21. … read more
The 22nd Meeting of the International Society for Molecular Recognition, the Affinity 2017, took place at the Pierre and Marie Curie Campus in Paris, France, from 25th to 29th of June. About 130 participants from academia and industry met to review advances in the field of (bio-)molecular recognition and affinity technology. … read more
A fast and reliable characterisation of protein-protein interactions is essential for various applications in both academic research as well as the chemical and pharmaceutical industry. Label-free technologies do not require a labelling with a reporter substance and enable a real-time monitoring and the determination of kinetic parameters. Many label-free biosensor systems however suffer from a low throughput read-out. … read more
Dr. Günter Roth from the University of Freiburg presented his latest results on “Label-free real-time imaging and detection of cell-free protein microarray synthesis and interaction analysis in an integrated microfluidic system” at BITE 2017. … read more
Find out about our latest products and applications at the APS from June 17 to 22. … read more
This year’s PEGS in Boston glittered by excellent scientific contributions and discussions. Even though the felt number of attendees did not completely meet the records of the organisers – at least during the exhibition – it was great to be there. … read more
Characterisation of cell surface antigens and their interaction partners is one of the hot topics in scientific research and development. The commonly applied biochemical approaches have certain limitations which might be overcome by label-free technologies. … read more
A fast but reliable identification of pathogens causing acute infections is a highly important issue in microbiological diagnostics. Conventional culture-based methods are well adapted and quite inexpensive but time-consuming and accompanied by certain limitations. Modern molecular methods have been increasingly incorporated in laboratories, but can they fully replace the traditional microbiological diagnostics? This article will focus on bacterial identification and characterisation methods in microbiological diagnostics including currently used technologies with their advantages and drawbacks. An overview table of the article will summarise all important information. … read more
Label-free detection technologies may suffer from non-specific binding of irrelevant proteins within the sample. Functionalisation of the sensor surface with specific (bio)polymers can inhibit this non-specific binding to a minimum. … read more
We are happy to announce a new joint project on label-free investigation of cell signal transduction. We are looking forward to the cooperation with Prof. Dr. Evi Kostenis and her group at University of Bonn. The project starts on 1st of April 2017 and is funded by: Bundesministerium für Wirtschaft und Energie (BMWi).
Our CEO Günther Proll will give a talk on “Label-free microarrays for the optimisation of protein and antibody binding” at the upcoming 8th Alpbach Workshop on Affinity Proteomics. Don’t miss the opportunity to join this dedicated meeting from March 13-15th in the Austrian Alps. Meet Günther to discuss our latest developments and applications for proteomic research.
Find out about the technology behind label-free microarrays and it’s multiple applications. Guest speaker Dr. Günter Roth (University of Freiburg) will give us insight on how he applies the SCORE technology in the development of diagnostic assays.
We proudly announce that the iGEM team we supported in the last year, has published an article in the current issue of BIOspektrum. Find out more about cell free protein synthesis.