Applications, Knowledge — February 7th, 2019

The potential of label-free screening in drug development

Single colour reflectometry – short SCORE – can be used to analyse the binding characteristics of hundreds to thousands biomolecular interactions without the need for labels. In the past years, label-free kinetic analysis used to be available only for a few lead candidates at the end of a pharmaceutical development process. But with a high throughput technology like SCORE it now is affordable to screen a high number of candidates at the beginning of the development of therapeutic antibodies. … read more