We bring label-free interaction studies to the next level
The potential of label-free screening in drug development
Single colour reflectometry – short SCORE – can be used to analyse the binding characteristics of hundreds to thousands biomolecular interactions without the need for labels. In the past years, label-free kinetic analysis used to be available only for a few lead candidates at the end of a pharmaceutical development process. But with a high throughput technology like SCORE it now is affordable to screen a high number of candidates at the beginning of the development of therapeutic antibodies. (more…)Read all news
The start-up Biametrics GmbH uses an enhanced version of reflectometry as a label-free tool to monitor biomolecular interactions, offering advantages over other optical detection methods. Besides a robust portable device, they have developed a rather sophisticated parallelized system, which allows time-resolved interaction analysis of up to 10,000 spots per cm^2 in a flexible/scalable array format. Furthermore, they are experts in the design and tailoring of specific affinity sensor surfaces, biomolecule targeting and data evaluation of kinetic and thermodynamic data.
Prof. Dr. G. Gauglitz, Institute of Physical and Theoretical Chemistry
Eberhard Karls University Tübingen